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CATH Superfamily 3.40.800.10

Ureohydrolase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ureohydrolase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Agmatinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanidinobutyrase activity GO:0047971
Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea.
 7 Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA)
Agmatinase activity GO:0008783
Catalysis of the reaction: agmatine + H(2)O = putrescine + urea.
 2 Q9BSE5 (/TAS) Q9BSE5 (/TAS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
 7 Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA) Q9I3S3 (/IDA)
Agmatine biosynthetic process GO:0097055
The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.
 2 Q9BSE5 (/TAS) Q9BSE5 (/TAS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
 2 Q9BSE5 (/TAS) Q9BSE5 (/TAS)