The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Isochorismatase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: Bifunctional pyrazinamidase/nicotinamidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nicotinamidase activity GO:0008936
Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.
17 P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA) P21369 (/IDA)
(7 more)
Nicotinamidase activity GO:0008936
Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.
9 Q54BH7 (/ISS) Q5LWN6 (/ISS) Q603P2 (/ISS) Q74AR2 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
7 Q603P2 (/ISS) Q74AR2 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyridine nucleotide salvage GO:0019365
Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.
17 P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP) P21369 (/IMP)
(7 more)
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
7 Q603P2 (/ISS) Q74AR2 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS) Q9KLN1 (/ISS)
Nicotinate nucleotide salvage GO:0019358
The generation of nicotinate nucleotide without de novo synthesis.
1 Q5LWN6 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.