The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 320: ubiquitin-like modifier-activating enzyme 7
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ISG15 activating enzyme activity GO:0019782
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
|
4 | P41226 (/IDA) Q8BTN4 (/IDA) Q9DBK7 (/IDA) Q9ET02 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | Q8BTN4 (/ISO) Q9DBK7 (/ISO) Q9ET02 (/ISO) |
|
ISG15 activating enzyme activity GO:0019782
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
|
3 | Q8BTN4 (/ISO) Q9DBK7 (/ISO) Q9ET02 (/ISO) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | P41226 (/EXP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P41226 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ISG15-protein conjugation GO:0032020
The covalent addition to a protein of ISG15, a ubiquitin-like protein.
|
4 | P41226 (/IDA) Q8BTN4 (/IDA) Q9DBK7 (/IDA) Q9ET02 (/IDA) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
3 | Q8BTN4 (/ISO) Q9DBK7 (/ISO) Q9ET02 (/ISO) |
|
Modification-dependent protein catabolic process GO:0019941
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
|
3 | Q8BTN4 (/IDA) Q9DBK7 (/IDA) Q9ET02 (/IDA) |
|
ISG15-protein conjugation GO:0032020
The covalent addition to a protein of ISG15, a ubiquitin-like protein.
|
3 | Q8BTN4 (/IMP) Q9DBK7 (/IMP) Q9ET02 (/IMP) |
|
ISG15-protein conjugation GO:0032020
The covalent addition to a protein of ISG15, a ubiquitin-like protein.
|
3 | Q8BTN4 (/ISO) Q9DBK7 (/ISO) Q9ET02 (/ISO) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
1 | P41226 (/IDA) |
|
Negative regulation of type I interferon production GO:0032480
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
1 | P41226 (/TAS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | P41226 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P41226 (/TAS) |