The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"HUPs
".
FunFam 27: Cysteine--tRNA ligase, cytoplasmic
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
11 |
Q09860 (/ISS)
Q291L4 (/ISS)
Q4R550 (/ISS)
Q54KR1 (/ISS)
Q5F408 (/ISS)
Q5F408 (/ISS)
Q5M7N8 (/ISS)
Q7KN90 (/ISS)
Q7ZWR2 (/ISS)
Q7ZWR2 (/ISS)
(1 more) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
10 | Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q5F408 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
3 | P49589 (/IDA) P49589 (/IDA) P53852 (/IDA) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
2 | P49589 (/IMP) P49589 (/IMP) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
2 | P49589 (/NAS) P49589 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P49589 (/IPI) P49589 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | P49589 (/IDA) P49589 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | P49589 (/IMP) P49589 (/IMP) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | Q9ER72 (/ISO) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
1 | Q9ER72 (/ISO) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
1 | Q7KN90 (/TAS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9ER72 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9ER72 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
11 |
Q09860 (/ISS)
Q291L4 (/ISS)
Q4R550 (/ISS)
Q54KR1 (/ISS)
Q5F408 (/ISS)
Q5F408 (/ISS)
Q5M7N8 (/ISS)
Q7KN90 (/ISS)
Q7ZWR2 (/ISS)
Q7ZWR2 (/ISS)
(1 more) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
3 | P49589 (/IDA) P49589 (/IDA) P53852 (/IDA) |
|
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
|
2 | P49589 (/TAS) P49589 (/TAS) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
1 | Q09860 (/NAS) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
1 | Q9ER72 (/ISO) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
|
1 | Q7KN90 (/TAS) |
|
Gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0021828
The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.
|
1 | E7FC09 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
17 |
A0A024RCG3 (/IDA)
A0A024RCG3 (/IDA)
B4DKY1 (/IDA)
P49589 (/IDA)
P49589 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
(7 more) |
|
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
|
12 |
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
Q8IJP3 (/IDA)
(2 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
10 | Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q5F408 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P49589 (/IDA) P49589 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q4QGR8 (/ISO) Q9ER72 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P49589 (/TAS) P49589 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P53852 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q7KN90 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q09860 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9ER72 (/ISO) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q54KR1 (/HDA) |