The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 132: Cytoplasmic tRNA 2-thiolation protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
6 A5E3Q3 (/ISS) A8WR63 (/ISS) B1WBV0 (/ISS) O76365 (/ISS) Q0VC66 (/ISS) Q99J10 (/ISS)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 O76365 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q7Z7A3 (/IPI)
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
1 O76365 (/IMP)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
6 A5E3Q3 (/ISS) A8WR63 (/ISS) B1WBV0 (/ISS) O76365 (/ISS) Q0VC66 (/ISS) Q99J10 (/ISS)
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
6 A5E3Q3 (/ISS) A8WR63 (/ISS) B1WBV0 (/ISS) O76365 (/ISS) Q0VC66 (/ISS) Q99J10 (/ISS)
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
1 O76365 (/IGI)
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
1 O76365 (/IMP)
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
1 Q7Z7A3 (/NAS)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
1 Q7Z7A3 (/TAS)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
1 O76365 (/IGI)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
1 O76365 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 O76365 (/IGI)
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
1 O76365 (/IMP)
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
1 Q7Z7A3 (/NAS)
Vulval development GO:0040025
The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
1 O76365 (/IGI)
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
1 O76365 (/IGI)
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 O76365 (/IGI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 A5E3Q3 (/ISS) A8WR63 (/ISS) B1WBV0 (/ISS) O76365 (/ISS) Q0VC66 (/ISS) Q7Z7A3 (/ISS) Q99J10 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q99J10 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q7Z7A3 (/TAS)