The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"von Willebrand factor, type A domain
".
FunFam 17: Anthrax toxin receptor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9H6X2 (/IPI) Q9H6X2 (/IPI) Q9H6X2 (/IPI) |
|
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
1 | Q9CZ52 (/ISO) |
|
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
1 | Q9CZ52 (/ISS) |
|
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | Q9CZ52 (/ISO) |
|
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | Q9CZ52 (/ISS) |
|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q9CZ52 (/ISO) |
|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q9CZ52 (/ISS) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q9CZ52 (/IMP) |
|
Reproductive process GO:0022414
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
|
1 | Q9CZ52 (/IMP) |
|
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q9CZ52 (/ISO) |
|
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q9CZ52 (/ISS) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
1 | Q9CZ52 (/ISO) |
|
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
|
1 | Q9CZ52 (/ISS) |
|
Negative regulation of extracellular matrix assembly GO:1901202
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.
|
1 | Q9CZ52 (/IMP) |
|
Positive regulation of metallopeptidase activity GO:1905050
Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.
|
1 | Q9CZ52 (/IMP) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q9H6X2 (/TAS) Q9H6X2 (/TAS) Q9H6X2 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q9H6X2 (/HDA) Q9H6X2 (/HDA) Q9H6X2 (/HDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
3 | Q9H6X2 (/TAS) Q9H6X2 (/TAS) Q9H6X2 (/TAS) |
|
Lamellipodium membrane GO:0031258
The portion of the plasma membrane surrounding a lamellipodium.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Filopodium membrane GO:0031527
The portion of the plasma membrane surrounding a filopodium.
|
3 | Q9H6X2 (/IDA) Q9H6X2 (/IDA) Q9H6X2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9CZ52 (/ISO) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q9CZ52 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q9CZ52 (/ISO) |
|
Lamellipodium membrane GO:0031258
The portion of the plasma membrane surrounding a lamellipodium.
|
1 | Q9CZ52 (/ISO) |
|
Lamellipodium membrane GO:0031258
The portion of the plasma membrane surrounding a lamellipodium.
|
1 | Q9CZ52 (/ISS) |
|
Filopodium membrane GO:0031527
The portion of the plasma membrane surrounding a filopodium.
|
1 | Q9CZ52 (/ISO) |
|
Filopodium membrane GO:0031527
The portion of the plasma membrane surrounding a filopodium.
|
1 | Q9CZ52 (/ISS) |