The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 647: Methylmalonic aciduria type A homolog, mitochondri...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
47 P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA) P27254 (/IDA)
(37 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
47 P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI) P27254 (/IPI)
(37 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q8IVH4 (/IMP) Q8IVH4 (/IMP)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q5MFW3 (/ISS) Q8C7H1 (/ISS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q8IVH4 (/IDA) Q8IVH4 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q5MFW3 (/ISS) Q8C7H1 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q8IVH4 (/IDA) Q8IVH4 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q5MFW3 (/ISS) Q8C7H1 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q8IVH4 (/IDA) Q8IVH4 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q5MFW3 (/ISS) Q8C7H1 (/ISS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q8C7H1 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q8C7H1 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8C7H1 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q8C7H1 (/ISO)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cobalamin metabolic process GO:0009235
The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
2 Q8IVH4 (/TAS) Q8IVH4 (/TAS)
Short-chain fatty acid catabolic process GO:0019626
The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.
2 Q8IVH4 (/TAS) Q8IVH4 (/TAS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q8IVH4 (/TAS) Q8IVH4 (/TAS)