The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 631: Ras small monomeric GTPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
3 P13856 (/IDA) P13856 (/IDA) P13856 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
6 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) P13856 (/IMP) P13856 (/IMP) P13856 (/IMP)
Cellular bud site selection GO:0000282
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Cytogamy GO:0000755
During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
3 P13856 (/IMP) P13856 (/IMP) P13856 (/IMP)
Axial cellular bud site selection GO:0007120
The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.
3 P13856 (/IMP) P13856 (/IMP) P13856 (/IMP)
Bipolar cellular bud site selection GO:0007121
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
3 P13856 (/IMP) P13856 (/IMP) P13856 (/IMP)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Thigmotropism GO:0009652
The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Maintenance of protein location in cell GO:0032507
Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
3 P13856 (/IGI) P13856 (/IGI) P13856 (/IGI)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Cellular response to electrical stimulus GO:0071257
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
3 A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP) A0A1D8PS50 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P52498 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) P13856 (/IDA) P13856 (/IDA) P13856 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
6 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) P13856 (/IDA) P13856 (/IDA) P13856 (/IDA)
Incipient cellular bud site GO:0000131
The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
3 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
3 P13856 (/HDA) P13856 (/HDA) P13856 (/HDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
3 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA)
Fungal-type cell wall GO:0009277
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
3 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA)
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
3 A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA) A0A1D8PS50 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
3 P13856 (/HDA) P13856 (/HDA) P13856 (/HDA)