The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 535: rac-like GTP-binding protein RAC2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
20 Q38912 (/IPI) Q38912 (/IPI) Q38912 (/IPI) Q38912 (/IPI) Q38912 (/IPI) Q38919 (/IPI) Q38919 (/IPI) Q38919 (/IPI) Q38937 (/IPI) Q38937 (/IPI)
(10 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
9 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38937 (/IDA) Q38937 (/IDA) Q38937 (/IDA) Q38937 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
5 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
5 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
4 Q38937 (/ISS) Q38937 (/ISS) Q38937 (/ISS) Q38937 (/ISS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
4 Q38937 (/TAS) Q38937 (/TAS) Q38937 (/TAS) Q38937 (/TAS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
4 Q38937 (/IPI) Q38937 (/IPI) Q38937 (/IPI) Q38937 (/IPI)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
3 Q38919 (/ISS) Q38919 (/ISS) Q38919 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
7 Q38919 (/IMP) Q38919 (/IMP) Q38919 (/IMP) Q38937 (/IMP) Q38937 (/IMP) Q38937 (/IMP) Q38937 (/IMP)
Positive gravitropism GO:0009958
The orientation of plant parts towards gravity.
5 Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP)
Regulation of auxin mediated signaling pathway GO:0010928
Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
5 Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP) Q38912 (/IMP)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 Q38919 (/IMP) Q38919 (/IMP) Q38919 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
3 Q38919 (/IGI) Q38919 (/IGI) Q38919 (/IGI)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
3 Q38919 (/IDA) Q38919 (/IDA) Q38919 (/IDA)
Plant-type secondary cell wall biogenesis GO:0009834
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
3 Q41253 (/TAS) Q41253 (/TAS) Q41254 (/TAS)
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
3 Q38919 (/IMP) Q38919 (/IMP) Q38919 (/IMP)
Secondary cell wall biogenesis involved in seed trichome differentiation GO:0090379
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
2 Q41253 (/IEP) Q41253 (/IEP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
20 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38937 (/IDA) Q38937 (/IDA)
(10 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38937 (/IDA) Q38937 (/IDA)
(2 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
12 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38937 (/IDA) Q38937 (/IDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
12 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38919 (/IDA) Q38937 (/IDA) Q38937 (/IDA)
(2 more)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
5 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA)
Site of polarized growth GO:0030427
Any part of a cell where non-isotropic growth takes place.
5 Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA) Q38912 (/IDA)
Phragmoplast GO:0009524
Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules.
4 Q38937 (/IDA) Q38937 (/IDA) Q38937 (/IDA) Q38937 (/IDA)