The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 514: Ribosome-releasing factor 2, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
18 A0JMI9 (/ISS) A6QNM2 (/ISS) A8WTI8 (/ISS) B0W010 (/ISS) B3M011 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS) B4JSI3 (/ISS) B4M416 (/ISS)
(8 more)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
11 A8WTI8 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS)
(1 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
10 Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q969S9 (/EXP) Q969S9 (/EXP)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q969S9 (/IDA) Q969S9 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q969S9 (/IPI) Q969S9 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q8R2Q4 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
17 A0JMI9 (/ISS) A6QNM2 (/ISS) B0W010 (/ISS) B3M011 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS) B4JSI3 (/ISS) B4M416 (/ISS) B4NAU8 (/ISS)
(7 more)
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
17 A0JMI9 (/ISS) A6QNM2 (/ISS) B0W010 (/ISS) B3M011 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS) B4JSI3 (/ISS) B4M416 (/ISS) B4NAU8 (/ISS)
(7 more)
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
10 Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS) Q8I592 (/ISS)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
2 Q969S9 (/IDA) Q969S9 (/IDA)
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
2 Q969S9 (/IDA) Q969S9 (/IDA)
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
2 Q969S9 (/TAS) Q969S9 (/TAS)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 Q8R2Q4 (/ISO)
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
1 Q8R2Q4 (/ISO)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
1 A8WTI8 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA) Q8I592 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q969S9 (/TAS) Q969S9 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R2Q4 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9VCX4 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O30913 (/IDA)