The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 500: ATP-dependent RNA helicase DHX29

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
2 A3KMI0 (/ISS) Q6PGC1 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q7Z478 (/HDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q581T1 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q4Q2M1 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q581T1 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q4Q2M1 (/ISO)
3'-5' RNA helicase activity GO:0034458
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.
1 Q581T1 (/IMP)
3'-5' RNA helicase activity GO:0034458
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.
1 Q4Q2M1 (/ISO)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
1 Q7Z478 (/IDA)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
1 Q6PGC1 (/ISO)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
1 Q7Z478 (/HDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial RNA processing GO:0000963
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
1 Q581T1 (/IC)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
1 Q581T1 (/IDA)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
1 Q4Q2M1 (/ISO)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q581T1 (/IMP)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q4Q2M1 (/ISO)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q581T1 (/IDA)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q4Q2M1 (/ISO)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
2 A3KMI0 (/ISS) Q6PGC1 (/ISS)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q581T1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q6PGC1 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q581T1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q581T1 (/RCA)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
1 Q7Z478 (/IDA)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
1 Q6PGC1 (/ISO)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
1 Q581T1 (/IDA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q581T1 (/IDA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q4Q2M1 (/ISO)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q581T1 (/RCA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q581T1 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q581T1 (/IDA)
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