The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 486: E3 ubiquitin-protein ligase TRIM23

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 17 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
16 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(6 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
15 P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS)
(5 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI)
(5 more)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
15 P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS) P36406 (/TAS)
(5 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
15 P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI) P36406 (/IPI)
(5 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 P36407 (/ISS) Q8BGX0 (/ISS)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
2 P36407 (/ISS) Q8BGX0 (/ISS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 P36407 (/ISS) Q8BGX0 (/ISS)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
2 P36407 (/ISS) Q8BGX0 (/ISS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q8BGX0 (/ISO)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q8BGX0 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q8BGX0 (/ISO)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
1 Q8BGX0 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8BGX0 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
2 P36407 (/ISS) Q8BGX0 (/ISS)
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
1 P36407 (/IDA)
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
1 Q8BGX0 (/ISO)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q8BGX0 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
15 P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA) P36406 (/IDA)
(5 more)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2 P36407 (/ISS) Q8BGX0 (/ISS)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
2 P36407 (/ISS) Q8BGX0 (/ISS)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q8BGX0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8BGX0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BGX0 (/IDA)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
1 Q8BGX0 (/ISO)