The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 462: Vitamin B12 import ATP-binding protein BtuD

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P06611 (/IPI) P06611 (/IPI) P06611 (/IPI) P06611 (/IPI) P06611 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
5 P06611 (/ISM) P06611 (/ISM) P06611 (/ISM) P06611 (/ISM) P06611 (/ISM)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
5 P06611 (/RCA) P06611 (/RCA) P06611 (/RCA) P06611 (/RCA) P06611 (/RCA)
ATPase-coupled vitamin B12 transmembrane transporter activity GO:0015420
Catalysis of the reaction: ATP(4-) + cob(I)alamin + H2O <=> ADP(3-) + hydrogenphosphate + cob(I)alamin + H+. Cobalamin is also known as vitamin B12.
5 P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA)
ATPase-coupled vitamin B12 transmembrane transporter activity GO:0015420
Catalysis of the reaction: ATP(4-) + cob(I)alamin + H2O <=> ADP(3-) + hydrogenphosphate + cob(I)alamin + H+. Cobalamin is also known as vitamin B12.
5 Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cobalamin transport GO:0015889
The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA)
Cobalamin transport GO:0015889
The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS) Q9KSL1 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
5 P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
5 P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA) P06611 (/IDA)