The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 427: Cytosolic Fe-S cluster assembly factor NUBP1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
14 A7RUD5 (/ISS) B0X4N8 (/ISS) Q16T79 (/ISS) Q24K00 (/ISS) Q3KQF0 (/ISS) Q3KQF0 (/ISS) Q5EB25 (/ISS) Q5I050 (/ISS) Q5I050 (/ISS) Q5I0L4 (/ISS)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P52920 (/IPI) P52920 (/IPI) P52920 (/IPI) P52920 (/IPI) P52920 (/IPI) P52920 (/IPI) P52920 (/IPI) P53384 (/IPI) Q9R060 (/IPI)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
7 P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
7 P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
1 P53384 (/TAS)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 O94442 (/ISO)
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
1 P53384 (/IDA)
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
1 Q9R060 (/ISO)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
1 O94442 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
14 A7RUD5 (/ISS) B0X4N8 (/ISS) Q16T79 (/ISS) Q24K00 (/ISS) Q3KQF0 (/ISS) Q3KQF0 (/ISS) Q5EB25 (/ISS) Q5I050 (/ISS) Q5I050 (/ISS) Q5I0L4 (/ISS)
(4 more)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
8 P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P53384 (/IMP)
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
7 P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP) P52920 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 P53384 (/IMP)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q9R060 (/ISO)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
1 P53384 (/IMP)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
1 Q9R060 (/ISO)
Negative regulation of centrosome duplication GO:0010826
Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
1 Q9R060 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
1 Q9R060 (/ISO)
[4Fe-4S] cluster assembly GO:0044572
The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
1 O94442 (/ISO)
Centrosome localization GO:0051642
Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
1 Q9R060 (/IMP)
Protein localization to cell cortex GO:0072697
A process in which a protein is transported to, or maintained in, the cell cortex.
1 Q9R060 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
14 A7RUD5 (/ISS) B0X4N8 (/ISS) Q16T79 (/ISS) Q24K00 (/ISS) Q3KQF0 (/ISS) Q3KQF0 (/ISS) Q5EB25 (/ISS) Q5I050 (/ISS) Q5I050 (/ISS) Q5I0L4 (/ISS)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 P52920 (/TAS) P52920 (/TAS) P52920 (/TAS) P52920 (/TAS) P52920 (/TAS) P52920 (/TAS) P52920 (/TAS)
Nbp35-Cfd1 ATPase complex GO:1904564
An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1.
7 P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA) P52920 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O94442 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94442 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P53384 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9R060 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P53384 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9R060 (/ISO)