The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 407: Rho-related GTP-binding protein RhoE

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
101 P52198 (/IPI) P52198 (/IPI) P52198 (/IPI) P52198 (/IPI) P61587 (/IPI) P61587 (/IPI) P61587 (/IPI) P61587 (/IPI) P61587 (/IPI) P61587 (/IPI)
(91 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
51 P52198 (/TAS) P52198 (/TAS) P52198 (/TAS) P52198 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS)
(41 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
47 P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS)
(37 more)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2 Q9QYM5 (/ISO) Q9QYM5 (/ISO)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q5HZE6 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
47 P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS)
(37 more)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
47 P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS) P61587 (/TAS)
(37 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
4 P52198 (/TAS) P52198 (/TAS) P52198 (/TAS) P52198 (/TAS)
Positive regulation of collateral sprouting GO:0048672
Any process that activates or increases the frequency, rate or extent of collateral sprouting.
2 Q9QYM5 (/IMP) Q9QYM5 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
47 P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA) P61587 (/HDA)
(37 more)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2 Q9QYM5 (/ISO) Q9QYM5 (/ISO)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q5HZE6 (/IDA)