The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 386: Regulator of nonsense transcripts 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
5 | P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
5 | P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
5 | P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) |
|
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
|
5 | P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
1 | Q09820 (/ISO) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q09820 (/IC) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Nuclear-transcribed mRNA catabolic process GO:0000956
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Regulation of translational termination GO:0006449
Any process that modulates the frequency, rate or extent of translational termination.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Intracellular mRNA localization GO:0008298
Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
5 | P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
5 | P30771 (/IPI) P30771 (/IPI) P30771 (/IPI) P30771 (/IPI) P30771 (/IPI) |
|
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
|
5 | P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) |
|
Nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070478
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
|
5 | P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) P30771 (/IGI) |
|
Nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070478
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
|
5 | P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) P30771 (/IMP) |
|
Nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070478
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
|
1 | Q09820 (/ISO) |
|
Regulation of mRNA stability involved in response to oxidative stress GO:2000815
A process of regulation of mRNA stability that is involved in a response to oxidative stress.
|
1 | Q09820 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) P30771 (/HDA) |
|
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
5 | P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) P30771 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q09820 (/HDA) |