The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 370: Structural maintenance of chromosomes 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
44 |
O42649 (/IPI)
O93309 (/IPI)
P47037 (/IPI)
P47037 (/IPI)
Q9CW03 (/IPI)
Q9CW03 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
(34 more) |
|
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
38 |
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
(28 more) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
38 |
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
Q9UQE7 (/IPI)
(28 more) |
|
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | A0A0R4ITA5 (/IPI) B2GRT6 (/IPI) Q1LVV8 (/IPI) Q803N2 (/IPI) |
|
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
|
4 | O97594 (/ISS) P97690 (/ISS) Q9CW03 (/ISS) Q9CW03 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
3 | Q56YN8 (/IDA) Q9CW03 (/IDA) Q9CW03 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
3 | Q24098 (/ISS) Q552D9 (/ISS) Q9VXE9 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | Q24098 (/ISS) Q9VXE9 (/ISS) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | P47037 (/IPI) P47037 (/IPI) |
|
Mediator complex binding GO:0036033
Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
|
2 | Q9CW03 (/IDA) Q9CW03 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P47037 (/IPI) P47037 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Dynein complex binding GO:0070840
Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | O42649 (/IMP) |
|
Cohesin ATPase activity GO:0061775
Catalysis of the reaction: ATP + H2O = ADP + phosphate, coupled to the topological linking or unlinking of a cohesin ring complex around homologous chromosomes.'
|
1 | O42649 (/IDA) |
There are 39 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
44 |
O93309 (/ISS)
O97594 (/ISS)
P97690 (/ISS)
Q552D9 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
(34 more) |
|
Sister chromatid cohesion GO:0007062
The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
|
39 |
Q56YN8 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
(29 more) |
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
38 |
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(28 more) |
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
38 |
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
(28 more) |
|
Sister chromatid cohesion GO:0007062
The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
|
38 |
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
(28 more) |
|
Negative regulation of DNA endoreduplication GO:0032876
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
|
38 |
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
(28 more) |
|
Positive regulation by host of viral release from host cell GO:0044791
A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Interaction with symbiont GO:0051702
An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Regulation of mitotic spindle assembly GO:1901673
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
|
38 |
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
Q9UQE7 (/IMP)
(28 more) |
|
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
|
5 | A0A0R4ITA5 (/IMP) B2GRT6 (/IMP) O42649 (/IMP) Q1LVV8 (/IMP) Q803N2 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
4 | A0A0R4ITA5 (/IMP) B2GRT6 (/IMP) Q1LVV8 (/IMP) Q803N2 (/IMP) |
|
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
4 | O97594 (/ISS) P97690 (/ISS) Q9CW03 (/ISS) Q9CW03 (/ISS) |
|
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
|
3 | Q8AWB8 (/TAS) Q8AWB8 (/TAS) Q8AWB8 (/TAS) |
|
Establishment of imaginal disc-derived wing hair orientation GO:0001737
Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
|
2 | Q24098 (/IMP) Q9VXE9 (/IMP) |
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
2 | Q00737 (/IMP) Q56YN8 (/IMP) |
|
Sister chromatid cohesion GO:0007062
The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
|
2 | P47037 (/IGI) P47037 (/IGI) |
|
Synaptonemal complex assembly GO:0007130
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
|
2 | P47037 (/IMP) P47037 (/IMP) |
|
Reciprocal meiotic recombination GO:0007131
The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
|
2 | P47037 (/IMP) P47037 (/IMP) |
|
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
2 | Q24098 (/IMP) Q9VXE9 (/IMP) |
|
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
2 | Q9CW03 (/IMP) Q9CW03 (/IMP) |
|
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
|
2 | P47037 (/IMP) P47037 (/IMP) |
|
Negative regulation of DNA endoreduplication GO:0032876
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Positive regulation by host of viral release from host cell GO:0044791
A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Meiotic sister chromatid cohesion GO:0051177
The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.
|
2 | P47037 (/IMP) P47037 (/IMP) |
|
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
2 | Q9CW03 (/IPI) Q9CW03 (/IPI) |
|
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Interaction with symbiont GO:0051702
An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Regulation of mitotic spindle assembly GO:1901673
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Replication-born double-strand break repair via sister chromatid exchange GO:1990414
The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.
|
2 | P47037 (/IMP) P47037 (/IMP) |
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q00737 (/IGI) |
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q00737 (/IMP) |
|
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
|
1 | Q552D9 (/ISS) |
|
Mitotic cohesin loading GO:0061780
The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.
|
1 | O42649 (/IDA) |
|
Mitotic cohesin loading GO:0061780
The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.
|
1 | O42649 (/IMP) |
|
Mitotic cohesin ssDNA (lagging strand) loading GO:0062022
The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.
|
1 | O42649 (/IDA) |
|
Maintenance of mitotic sister chromatid cohesion, centromeric GO:0071960
The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
|
1 | O42649 (/IMP) |
There are 41 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
44 |
O93309 (/ISS)
O97594 (/ISS)
P97690 (/ISS)
Q552D9 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
(34 more) |
|
Cohesin complex GO:0008278
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
|
44 |
B2FDA8 (/IDA)
O42649 (/IDA)
Q24098 (/IDA)
Q9CW03 (/IDA)
Q9CW03 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(34 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
43 |
Q8AWB8 (/TAS)
Q8AWB8 (/TAS)
Q8AWB8 (/TAS)
Q9CW03 (/TAS)
Q9CW03 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(33 more) |
|
Meiotic cohesin complex GO:0030893
A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
|
43 |
O93309 (/ISS)
O97594 (/ISS)
P97690 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
Q5R4K5 (/ISS)
(33 more) |
|
Cohesin complex GO:0008278
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
|
40 |
Q24098 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
Q9UQE7 (/NAS)
(30 more) |
|
Meiotic cohesin complex GO:0030893
A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
|
40 |
Q9CW03 (/IDA)
Q9CW03 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(30 more) |
|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
39 |
Q56YN8 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(29 more) |
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
39 |
P97690 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(29 more) |
|
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
|
39 |
Q56YN8 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(29 more) |
|
Chromosome, centromeric region GO:0000775
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
38 |
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(28 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
38 |
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(28 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
38 |
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(28 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
38 |
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
Q9UQE7 (/TAS)
(28 more) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
38 |
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
Q9UQE7 (/IDA)
(28 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | P47037 (/IDA) P47037 (/IDA) Q56YN8 (/IDA) Q9CW03 (/IDA) Q9CW03 (/IDA) |
|
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
|
4 | O97594 (/ISS) P97690 (/ISS) Q9CW03 (/ISS) Q9CW03 (/ISS) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
4 | O97594 (/ISS) P97690 (/ISS) Q9CW03 (/ISS) Q9CW03 (/ISS) |
|
Nuclear mitotic cohesin complex GO:0034990
A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.
|
3 | O42649 (/IDA) P47037 (/IDA) P47037 (/IDA) |
|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Lateral element GO:0000800
A proteinaceous core found between sister chromatids during meiotic prophase.
|
2 | Q9CW03 (/IDA) Q9CW03 (/IDA) |
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Cohesin complex GO:0008278
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Cohesin complex GO:0008278
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
|
2 | Q552D9 (/ISS) Q56YN8 (/ISS) |
|
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Meiotic cohesin complex GO:0030893
A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Nuclear meiotic cohesin complex GO:0034991
A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
|
2 | Q9CW03 (/IDA) Q9CW03 (/IDA) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
2 | Q9CW03 (/ISO) Q9CW03 (/ISO) |
|
Condensed nuclear chromosome, centromeric region GO:0000780
The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
1 | O42649 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | B2FDA8 (/IDA) |
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
1 | P97690 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O42649 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q552D9 (/ISS) |
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
1 | O42649 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q56YN8 (/IDA) |
|
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
1 | Q56YN8 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O42649 (/HDA) |
|
Cohesin complex GO:0008278
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
|
1 | B2FDA8 (/IPI) |
|
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
1 | Q56YN8 (/IDA) |
|
Mitotic cohesin complex GO:0030892
A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.
|
1 | O42649 (/IDA) |