The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 32: Export ABC transporter ATP-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
63 A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS) A0A0J1HS36 (/ISS)
(53 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI)
(1 more)
ATPase-coupled xenobiotic transmembrane transporter activity GO:0008559
Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
ATPase-coupled xenobiotic transmembrane transporter activity GO:0008559
Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
11 P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA) P75831 (/RCA)
(1 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
11 P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI) P75831 (/IPI)
(1 more)
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
5 Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q881Q1 (/ISS) Q881Q1 (/ISS)
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
2 Q9I190 (/IDA) Q9I190 (/IDA)
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
2 Q9I190 (/IMP) Q9I190 (/IMP)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Drug export GO:0046618
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
Drug export GO:0046618
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
11 P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP) P75831 (/IMP)
(1 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
7 Q881Q1 (/ISS) Q881Q1 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
6 P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP)
Response to host immune response GO:0052572
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
6 P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP) P9WQK1 (/IMP)
Pyoverdine biosynthetic process GO:0002049
The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
2 Q9I190 (/IMP) Q9I190 (/IMP)
Lipoprotein modification GO:0042160
The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
1 Q5LUD0 (/ISS)
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q5LUD0 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
MacAB-TolC complex GO:1990196
The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.
11 P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA) P75831 (/IDA)
(1 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
7 Q881Q1 (/ISS) Q881Q1 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS) Q884D4 (/ISS)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
5 Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA) Q8UFV7 (/ISA)
Efflux pump complex GO:1990281
A protein complex that is capable of efflux transmembrane transporter activity.
2 Q9I190 (/IDA) Q9I190 (/IDA)
Efflux pump complex GO:1990281
A protein complex that is capable of efflux transmembrane transporter activity.
2 Q9I190 (/IMP) Q9I190 (/IMP)