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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 253: Peptide chain release factor 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
 43 P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA)
(33 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 43 P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI) P0A7I4 (/IPI)
(33 more)
Translation release factor activity, codon nonspecific GO:0016150
A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
 43 P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA)
(33 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
 43 P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA)
(33 more)
Translation release factor activity GO:0003747
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
 5 Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
 43 P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA)
(33 more)
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
 5 Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS) Q9KU64 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 43 P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA) P0A7I4 (/IDA)
(33 more)