The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Succinyl-CoA synthetase domains
".
FunFam 6: Succinate--CoA ligase [ADP-forming] subunit alpha
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Succinate-CoA ligase (ADP-forming) activity GO:0004775
Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.
|
2 | P53598 (/IDA) P53598 (/IDA) |
|
Succinate-CoA ligase (ADP-forming) activity GO:0004775
Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.
|
2 | P53598 (/IMP) P53598 (/IMP) |
|
Malate-CoA ligase activity GO:0050074
Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.
|
1 | Q5LT45 (/ISS) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
2 | P53598 (/TAS) P53598 (/TAS) |
|
Succinyl-CoA metabolic process GO:0006104
The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.
|
2 | P53598 (/IDA) P53598 (/IDA) |
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
1 | Q5LT45 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
5 | P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) P9WGC7 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P53598 (/HDA) P53598 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P53598 (/IDA) P53598 (/IDA) |
|
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
|
2 | P53598 (/IDA) P53598 (/IDA) |