The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
alpha/beta hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 69: monoacylglycerol lipase ABHD12

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipase activity GO:0004620
Catalysis of the hydrolysis of a glycerophospholipid.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Phospholipase activity GO:0004620
Catalysis of the hydrolysis of a glycerophospholipid.
2 Q8N2K0 (/IDA) Q8N2K0 (/IDA)
Phospholipase activity GO:0004620
Catalysis of the hydrolysis of a glycerophospholipid.
1 Q99LR1 (/ISO)
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
1 Q99LR1 (/IMP)
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
1 Q99LR1 (/ISO)
Palmitoyl-(protein) hydrolase activity GO:0008474
Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.
1 Q99LR1 (/IDA)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
1 Q99LR1 (/ISO)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylserine catabolic process GO:0006660
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Monoacylglycerol catabolic process GO:0052651
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Monoacylglycerol catabolic process GO:0052651
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Phosphatidylserine catabolic process GO:0006660
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
2 Q8N2K0 (/IDA) Q8N2K0 (/IDA)
Glycerophospholipid catabolic process GO:0046475
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
2 Q8N2K0 (/IDA) Q8N2K0 (/IDA)
Protein depalmitoylation GO:0002084
The removal of palymitoyl groups from a lipoprotein.
1 Q99LR1 (/IDA)
Phosphatidylserine catabolic process GO:0006660
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 Q99LR1 (/IMP)
Phosphatidylserine catabolic process GO:0006660
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 Q99LR1 (/ISO)
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
1 Q99LR1 (/IMP)
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
1 Q99LR1 (/IMP)
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
1 Q99LR1 (/ISO)
Retina layer formation GO:0010842
The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
1 Q08C93 (/IMP)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
1 Q99LR1 (/IMP)
Swimming behavior GO:0036269
The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.
1 Q08C93 (/IMP)
Myelination GO:0042552
The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
1 Q08C93 (/IMP)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
1 Q08C93 (/IMP)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
1 Q99LR1 (/ISO)
Glycerophospholipid catabolic process GO:0046475
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 Q99LR1 (/ISO)
Anterior lateral line development GO:0048899
The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
1 Q08C93 (/IMP)
Posterior lateral line neuromast development GO:0048919
The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
1 Q08C93 (/IMP)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
1 Q99LR1 (/IMP)
Monoacylglycerol catabolic process GO:0052651
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
1 Q99LR1 (/ISO)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS) Q8N2K0 (/ISS)
(1 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
9 B4F753 (/ISS) Q08C93 (/ISS) Q08DW9 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q4R766 (/ISS) Q5ZIN0 (/ISS) Q6AYT7 (/ISS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
3 Q8N2K0 (/IDA) Q8N2K0 (/IDA) Q99LR1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8N2K0 (/TAS) Q8N2K0 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99LR1 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q99LR1 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q99LR1 (/IDA)
AMPA glutamate receptor complex GO:0032281
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
1 Q99LR1 (/IDA)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
1 Q99LR1 (/IDA)