The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
alpha/beta hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53: Abhydrolase domain containing 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
2 P08910 (/IDA) P08910 (/IDA)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
2 P08910 (/IDA) P08910 (/IDA)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
2 P08910 (/IDA) P08910 (/IDA)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 Q9QXM0 (/ISO)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
1 Q9QXM0 (/ISO)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
1 Q9QXM0 (/ISO)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
21 Q05AK6 (/ISS) Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS) Q4R2Y9 (/ISS)
(11 more)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
4 Q5EA42 (/ISS) Q5EA42 (/ISS) Q5EA42 (/ISS) Q5EA42 (/ISS)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
4 Q5EA42 (/ISS) Q5EA42 (/ISS) Q5EA42 (/ISS) Q5EA42 (/ISS)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
2 P08910 (/IDA) P08910 (/IDA)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
2 P08910 (/IDA) P08910 (/IDA)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
2 P08910 (/IDA) P08910 (/IDA)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
2 P08910 (/IDA) P08910 (/IDA)
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
1 Q9QXM0 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q9QXM0 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q9QXM0 (/IMP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 Q9QXM0 (/ISO)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
1 Q9QXM0 (/ISO)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
1 Q9QXM0 (/ISO)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 Q9QXM0 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
2 P08910 (/IDA) P08910 (/IDA)
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
2 P08910 (/IDA) P08910 (/IDA)
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
1 Q9QXM0 (/IDA)
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
1 Q9QXM0 (/ISO)
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
1 Q9QXM0 (/ISO)