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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
alpha/beta hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 376: Probable carboxylesterase 12

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Carboxylesterase. [EC: 3.1.1.1]
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
  • Wide specificity; also hydrolyzes vitamin A esters.
  • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4 and EC 3.5.1.13.
  • Formerly EC 3.1.1.12.
 8 A0A0R0LP27 A0A0R0LP27 Q5NUF3 Q5NUF3 Q5NUF4 Q9FX94 Q9SMM9 Q9SMN0
2-hydroxyisoflavanone dehydratase. [EC: 4.2.1.105]
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H(2)O. (2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H(2)O.
  • Catalyzes the final step in the formation of the isoflavonoid skeleton.
  • The reaction also occurs spontaneously.
 5 A0A0R0LP27 A0A0R0LP27 Q5NUF3 Q5NUF3 Q5NUF4