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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 86: Demethylmenaquinone methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Demethylmenaquinone methyltransferase. [EC: 2.1.1.163]
A demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine.
  • The enzyme catalyzes the last step in menaquinone biosynthesis.
  • It is able to accept substrates with varying polyprenyl side chain length (the chain length is determined by polyprenyl diphosphate synthase).
  • The enzyme from Escherichia coli also catalyzes the conversion of 2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3- octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone.
  • The enzyme probably acts on menaquinol rather than menaquinone.
 4859 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3 A0A023P4T3
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