The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Ribosomal RNA large subunit methyltransferase E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (uridine-2'-O-)-methyltransferase activity GO:0008650
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.
182 P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA)
(172 more)
RRNA methyltransferase activity GO:0008649
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
1 Q86AH1 (/ISS)
RRNA (uridine-2'-O-)-methyltransferase activity GO:0008650
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.
1 P78860 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
182 P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA)
(172 more)
Enzyme-directed rRNA 2'-O-methylation GO:0000453
The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA.
182 P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP) P0C0R7 (/IMP)
(172 more)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
1 P78860 (/ISO)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
1 Q86AH1 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
182 P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA) P0C0R7 (/IDA)
(172 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P78860 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q86AH1 (/ISS)