The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115: Cyclopropane mycolic acid synthase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cyclopropane-fatty-acyl-phospholipid synthase activity GO:0008825
Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
35 A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U866 (/IMP) A5U866 (/IMP) A5U866 (/IMP) A5U866 (/IMP) A5U866 (/IMP)
(25 more)
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
34 A5U027 (/IMP) A5U027 (/IMP) A5U027 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) A5U029 (/IMP) P9WPB1 (/IMP) P9WPB1 (/IMP)
(24 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P0CH91 (/IPI) P9WPB1 (/IPI) P9WPB1 (/IPI)
(18 more)
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
16 A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP)
(6 more)
Cyclopropane-fatty-acyl-phospholipid synthase activity GO:0008825
Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
16 P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA)
(6 more)
Cis-trans isomerase activity GO:0016859
Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
12 P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA)
(2 more)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
3 Q79FX8 (/IDA) Q79FX8 (/IDA) Q79FX8 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
56 A5U027 (/IMP) A5U027 (/IMP) A5U027 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP) A5U028 (/IMP)
(46 more)
Mycolic acid biosynthetic process GO:0071768
The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
53 P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P0CH91 (/IDA) P9WPB1 (/IDA) P9WPB1 (/IDA)
(43 more)
S-adenosylmethionine metabolic process GO:0046500
The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
25 P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB5 (/IDA)
(15 more)
Mycolic acid biosynthetic process GO:0071768
The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
22 P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) P0CH91 (/IMP) Q79FX6 (/IMP) Q79FX6 (/IMP)
(12 more)
Modulation by symbiont of host innate immune response GO:0052167
Any process in which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
20 P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB5 (/IMP)
(10 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
11 P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP) P9WPB5 (/IEP)
(1 more)
Actinobacterium-type cell wall biogenesis GO:0071766
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
11 P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA)
(1 more)
Mycolate cell wall layer assembly GO:0071769
The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.
11 P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA) P9WPB5 (/IDA)
(1 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
9 P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA) P9WPB3 (/IDA)
Active evasion of host immune response GO:0042783
Any mechanism of immune avoidance that directly affects the host immune system, e.g. blocking any stage in host MHC class I and II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
9 P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP) P9WPB3 (/IMP)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
5 P9WPB7 (/IDA) P9WPB7 (/IDA) P9WPB7 (/IDA) P9WPB7 (/IDA) P9WPB7 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
40 P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P0CH91 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA)
(30 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA) P9WPB5 (/HDA)
(1 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
8 Q79FX6 (/HDA) Q79FX6 (/HDA) Q79FX6 (/HDA) Q79FX6 (/HDA) Q79FX6 (/HDA) Q79FX8 (/HDA) Q79FX8 (/HDA) Q79FX8 (/HDA)