The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: HAD family hydrolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
117 Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS)
(107 more)
2-deoxyglucose-6-phosphatase activity GO:0003850
Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.
117 Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS)
(107 more)
Glucose-6-phosphatase activity GO:0004346
Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
117 Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS)
(107 more)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
117 Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS)
(107 more)
Sugar-phosphatase activity GO:0050308
Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.
117 Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS) Q7ADF8 (/ISS)
(107 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
2-deoxyglucose-6-phosphatase activity GO:0003850
Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Glucose-6-phosphatase activity GO:0004346
Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Mannitol-1-phosphatase activity GO:0050084
Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Sorbitol-6-phosphatase activity GO:0050286
Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Sugar-phosphatase activity GO:0050308
Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Hydrolase activity GO:0016787
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
6 Q9KN63 (/ISS) Q9KN63 (/ISS) Q9KN63 (/ISS) Q9KN63 (/ISS) Q9KN63 (/ISS) Q9KN63 (/ISS)

There are 0 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
27 P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA) P77247 (/IDA)
(17 more)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q680K2 (/IDA) Q94K71 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q680K2 (/IDA) Q94K71 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q680K2 (/IDA) Q94K71 (/IDA)