The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Uracil-DNA glycosylase-like domain
".
FunFam 3: G/U mismatch-specific DNA glycosylase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pyrimidine-specific mismatch base pair DNA N-glycosylase activity GO:0008263
Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
|
124 |
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
(114 more) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Base-excision repair, AP site formation GO:0006285
The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.
|
124 |
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
P0A9H1 (/IDA)
(114 more) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.