The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhodanese-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Sulfurtransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiosulfate sulfurtransferase activity GO:0004792
Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.
52 O64530 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA)
(42 more)
3-mercaptopyruvate sulfurtransferase activity GO:0016784
Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
52 O64530 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA)
(42 more)
Thiosulfate sulfurtransferase activity GO:0004792
Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.
9 O64530 (/ISS) Q24JL3 (/ISS) Q5LM45 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS)
5S rRNA binding GO:0008097
Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
6 P00586 (/ISS) P24329 (/ISS) P25324 (/ISS) P46635 (/ISS) P52196 (/ISS) P52196 (/ISS)
Thiosulfate sulfurtransferase activity GO:0004792
Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.
4 P25325 (/TAS) P25325 (/TAS) Q16762 (/TAS) Q16762 (/TAS)
3-mercaptopyruvate sulfurtransferase activity GO:0016784
Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
4 P25325 (/ISS) P25325 (/ISS) Q608D7 (/ISS) Q8EHG0 (/ISS)
5S rRNA binding GO:0008097
Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
2 Q16762 (/IDA) Q16762 (/IDA)
5S rRNA binding GO:0008097
Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
2 P52196 (/ISO) P52196 (/ISO)
3-mercaptopyruvate sulfurtransferase activity GO:0016784
Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
2 P25325 (/TAS) P25325 (/TAS)
Thiosulfate sulfurtransferase activity GO:0004792
Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.
1 Q99J99 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P00586 (/IPI)
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
1 O64530 (/IDA)
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
1 P24329 (/TAS)
3-mercaptopyruvate sulfurtransferase activity GO:0016784
Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
1 Q99J99 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P97532 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q99J99 (/ISO)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
49 P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP)
(39 more)
DNA protection GO:0042262
Any process in which DNA is protected from damage by, for example, oxidative stress.
49 P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP)
(39 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
49 P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP) P31142 (/IMP)
(39 more)
Sulfur compound metabolic process GO:0006790
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
9 Q5LM45 (/ISS) Q608D7 (/ISS) Q8EHG0 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS) Q9KLX1 (/ISS)
RRNA import into mitochondrion GO:0035928
The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol, into the mitochondrial matrix.
6 P00586 (/ISS) P24329 (/ISS) P25324 (/ISS) P46635 (/ISS) P52196 (/ISS) P52196 (/ISS)
RRNA transport GO:0051029
The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 P00586 (/ISS) P24329 (/ISS) P25324 (/ISS) P46635 (/ISS) P52196 (/ISS) P52196 (/ISS)
Sulfur amino acid catabolic process GO:0000098
The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
4 P25325 (/TAS) P25325 (/TAS) Q16762 (/TAS) Q16762 (/TAS)
Cyanate catabolic process GO:0009440
The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.
4 P25325 (/TAS) P25325 (/TAS) Q16762 (/TAS) Q16762 (/TAS)
Hydrogen sulfide biosynthetic process GO:0070814
The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
3 P25325 (/ISS) P25325 (/ISS) P97532 (/ISS)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
2 P25325 (/TAS) P25325 (/TAS)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
2 Q16762 (/IDA) Q16762 (/IDA)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
2 P52196 (/ISO) P52196 (/ISO)
RRNA import into mitochondrion GO:0035928
The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol, into the mitochondrial matrix.
2 Q16762 (/IMP) Q16762 (/IMP)
RRNA import into mitochondrion GO:0035928
The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol, into the mitochondrial matrix.
2 P52196 (/ISO) P52196 (/ISO)
RRNA transport GO:0051029
The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q16762 (/IDA) Q16762 (/IDA)
RRNA transport GO:0051029
The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P52196 (/ISO) P52196 (/ISO)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 P97532 (/IDA)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q99J99 (/ISO)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 P97532 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 Q99J99 (/ISO)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 Q24JL3 (/IGI)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 O64530 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
1 P24329 (/NAS)
Transsulfuration GO:0019346
The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
1 P97532 (/IDA)
Transsulfuration GO:0019346
The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
1 Q99J99 (/ISO)
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
1 P97532 (/IEP)
Hydrogen sulfide biosynthetic process GO:0070814
The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
1 Q99J99 (/IDA)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
51 P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA) P31142 (/IDA)
(41 more)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
5 P24329 (/TAS) P25325 (/TAS) P25325 (/TAS) Q16762 (/TAS) Q16762 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 O64530 (/IDA) P97532 (/IDA) Q16762 (/IDA) Q16762 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P52196 (/HDA) P52196 (/HDA) Q99J99 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P52196 (/ISO) P52196 (/ISO) Q99J99 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
3 P52196 (/HDA) P52196 (/HDA) Q99J99 (/HDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
3 P25325 (/ISS) P25325 (/ISS) P97532 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q16762 (/HDA) Q16762 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P97532 (/IDA) Q24JL3 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q16762 (/NAS) Q16762 (/NAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P25325 (/HDA) P25325 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99J99 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99J99 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q99J99 (/ISO)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 O64530 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q99J99 (/IDA)