The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Periplasmic binding protein-like II
".
FunFam 61: Glutamate receptor, ionotropic kainate
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Kainate selective glutamate receptor activity GO:0015277
An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
|
6 | Q0E8N6 (/ISS) Q5U168 (/ISS) Q8MS48 (/ISS) Q9V4A0 (/ISS) Q9VDH5 (/ISS) Q9VDH5 (/ISS) |
|
Glutamate-gated calcium ion channel activity GO:0022849
Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
|
2 | Q9VDH5 (/IMP) Q9VDH5 (/IMP) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of synaptic activity GO:0060025
Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
|
6 | Q0E8N6 (/ISS) Q5U168 (/ISS) Q8MS48 (/ISS) Q9V4A0 (/ISS) Q9VDH5 (/ISS) Q9VDH5 (/ISS) |
|
Calcium ion import across plasma membrane GO:0098703
The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
|
2 | Q9VDH5 (/IMP) Q9VDH5 (/IMP) |
|
Positive regulation of neuromuscular synaptic transmission GO:1900075
Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
|
2 | Q9VDH5 (/IMP) Q9VDH5 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | Q0E8N6 (/ISS) Q5U168 (/ISS) Q8MS48 (/ISS) Q9V4A0 (/ISS) Q9VDH5 (/ISS) Q9VDH5 (/ISS) |
|
Presynaptic active zone GO:0048786
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
|
2 | Q9VDH5 (/IDA) Q9VDH5 (/IDA) |