The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Calcium-transporting ATPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium transmembrane transporter activity, phosphorylative mechanism GO:0005388
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
9 O22218 (/ISS) O64806 (/ISS) O81108 (/ISS) O81108 (/ISS) O81108 (/ISS) Q37145 (/ISS) Q37145 (/ISS) Q9M2L4 (/ISS) Q9M2L4 (/ISS)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
4 O22218 (/IDA) O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Calcium transmembrane transporter activity, phosphorylative mechanism GO:0005388
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
3 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Calcium ion transmembrane transporter activity GO:0015085
Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.
3 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2 Q37145 (/TAS) Q37145 (/TAS)
Calcium transmembrane transporter activity, phosphorylative mechanism GO:0005388
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
2 Q37145 (/TAS) Q37145 (/TAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
3 O22218 (/IGI) Q9M2L4 (/IGI) Q9M2L4 (/IGI)
Negative regulation of programmed cell death GO:0043069
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
3 O22218 (/IGI) Q9M2L4 (/IGI) Q9M2L4 (/IGI)
Anion homeostasis GO:0055081
Any process involved in the maintenance of an internal steady state of anions within an organism or cell.
3 O22218 (/IMP) Q9M2L4 (/IMP) Q9M2L4 (/IMP)
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
3 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
1 O64806 (/IMP)
Response to nematode GO:0009624
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
1 O22218 (/IEP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 O64806 (/IDA) O81108 (/IDA) O81108 (/IDA) O81108 (/IDA) Q37145 (/IDA) Q37145 (/IDA) Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
5 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA) Q37145 (/IDA) Q37145 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
3 O22218 (/IDA) Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
3 O22218 (/IDA) Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
3 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 O22218 (/IDA) Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Plant-type vacuole membrane GO:0009705
The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
3 O22218 (/IDA) Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 O81108 (/IDA) O81108 (/IDA) O81108 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 Q9M2L4 (/IDA) Q9M2L4 (/IDA)
Chloroplast inner membrane GO:0009706
The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.
2 Q37145 (/IDA) Q37145 (/IDA)
Chloroplast inner membrane GO:0009706
The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.
2 Q37145 (/TAS) Q37145 (/TAS)
Plant-type vacuole GO:0000325
A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
1 O22218 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 O22218 (/TAS)