The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Bira Bifunctional Protein; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1112
3D
1lylC02 - 83.7
2
1069
3D
4p3pB01 - 92.0
3
1034
3D
4p75D01 - 92.9
4
973
3D
3hy1B01 - 92.6
5
754
3D
1qe0A01 - 88.6
6
751
3D
5f5wE01 - 80.0
7
695
3D
4k88A01 - 80.7
8
675 - - 79.9
9
649
3D
4ttvD01 - 92.7
10
591
3D
4kr3A01 - 82.9
11
587
3D
5v59A01 - 85.8
12
475
3D
5ucmB02 - 65.5
13
445
3D
4j15B02 - 83.8
14
396 - - 82.2
16
386 - - 88.4
15
385 - - 78.9
17
R
377
3D
3a5zG00 - 89.5
18
367
3D
6h9xA02 - 43.1
21
329
3D
4x5oA01 - 85.5
19
324 - - 89.8
20
323 - - 87.5
22
307
3D
3pcoD05 - 96.0
23
303
3D
1hc7D01 - 79.2
24
284
3D
4tvyB01 - 76.8
26
261
3D
6girA02 - 84.0
25
257
3D
12asB00 - 22.9
27
223
3D
4rqfB02 - 73.2
29
218
3D
6ilhB02 - 71.2
28
204 - - 74.6
30
204
3D
1il2B02 - 75.9
32
177 - - 85.1
31
177 - - 89.8
33
149 - - 71.7
34
140 - - 40.8
39
134
3D
4yyeB01 - 89.3
35
134
3D
1w66A01 - 94.8
37
134
3D
1nj8D01 - 90.8
38
132
3D
3nenB02 - 94.1
36
131
3D
3l4gM00 - 59.5
42
129
3D
2i4oC01 - 97.1
40
128
3D
5xixD02 - 80.9
41
126
3D
5mgwA01 - 76.8
43
110 - - 71.8
45
105
3D
3a7uA01 - 89.9
48
105
3D
2zr3B02 - 87.2
44
105 - - 66.1
46
102 - - 75.8
47
99
3D
1wleB02 - 68.2
50
97
3D
4wf2A02 - 71.2
49
96
3D
4ah6D02 - 69.6
57
89
3D
1g5iD01 - 77.1
51
86 - - 56.6
52
80 - - 79.2
53
75 - - 91.6
56
75
3D
3wqzB01 - 88.7
54
71 - - 89.1
55
66 - - 83.0
58
61 - - 36.7
60
60 - - 13.9
59
60 - - 88.3
62
58
3D
2j3mB02 - 25.8
61
58 - - 73.8
63
49 - - 75.1
64
48 - - 24.6
65
47 - - 84.2
66
45 - - 87.5
67
43 - - 65.7
68
40 - - 68.6
69
38 - - 79.9
70
37 - - 76.1
71
36 - - 25.5
72
35
3D
1vqzA01 - 89.0
79
33
3D
6aqgC02 - 45.0
73
33 - - 30.0
101
32
3D
5t8uB01 - 73.7
74
32 - - 91.7
75
32 - - 38.4
76
31 - - 84.0
77
28 - - 78.1
78
28 - - 83.2
81
28 - - 65.6
80
28 - - 60.3
82
27 - - 62.8
83
25 - - 71.0
84
24 - - 78.6
85
24 - - 41.0
87
23 - - 37.6
89
23 - - 69.5
86
23 - - 70.3
88
23 - - 72.9
94
22 - - 79.4
90
22 - - 78.1
93
22 - - 68.6
91
22 - - 72.4
92
22 - - 85.2
95
21 - - 86.5
96
20 - - 11.1
97
20 - - 81.1
98
19 - - 3.3
100
19 - - 4.0
99
19 - - 12.5
102
18 - - 12.7
104
18 - - 24.7
103
18 - - 4.7
106
18 - - 43.7
105
18 - - 23.9
113
17 - - 49.1
107
17 - - 77.4
109
17 - - 8.4
110
17 - - 11.6
112
17 - - 3.6
108
17 - - 78.7
114
17 - - 7.7
111
17 - - 14.2
118
16 - - 7.4
139
Cys
16
3D
2du7D03 - 52.5
119
16 - - 7.2
116
16 - - 7.5
120
16 - - 27.6
115
16 - - 7.9
117
16 - - 11.7
124
15 - - 20.9
122
15 - - 14.7
125
15 - - 76.8
165
15
3D
6o3fB02 - 10.6
121
15 - - 88.3
123
15 - - 17.6
127
14 - - 5.9
129
14 - - 7.7
126
14 - - 18.8
128
14 - - 2.5
130
14 - - 70.8
131
14 - - 67.1
135
13 - - 25.3
136
13 - - 17.5
138
13 - - 65.6
137
13 - - 0.0
132
13 - - 88.5
133
13 - - 33.1
134
13 - - 6.0
142
12 - - 14.4
140
12 - - 0.6
143
12 - - 72.6
141
12 - - 2.8
145
11 - - 10.6
144
11 - - 32.3
151
11 - - 63.5
150
11 - - 14.8
148
11 - - 32.1
147
11 - - 15.3
149
11 - - 10.6
146
11 - - 11.3
153
10 - - 59.4
152
10 - - 10.4
227
10
3D
3dsqB02 - 2.0
155
10 - - 0.5
154
10 - - 13.9
158
10 - - 93.9
157
10 - - 93.1
156
10 - - 47.6
160
9 - - 11.2
161
9 - - 2.9
167
9 - - 71.1
163
9 - - 25.3
159
9 - - 52.5
162
9 - - 70.8
166
9 - - 41.5
164
9 - - 6.4
168
8 - - 5.3
191
8
3D
3l2zB01 - 0.5
169
8 - - 18.8
178
7 - - 55.2
180
7 - - 46.1
177
7 - - 23.6
171
7 - - 3.9
176
7 - - 1.2
170
7 - - 6.8
175
7 - - 11.6
240
7
3D
1usyD00 - 78.1
174
7 - - 0.0
172
7 - - 35.7
179
7 - - 40.5
173
7 - - 0.0
189
6 - - 80.9
197
6
3D
4up8A02 - 25.4
187
6 - - 8.4
182
6 - - 3.2
184
DNA directed
6 - - 34.2
181
6 - - 22.0
188
6 - - 7.9
183
6 - - 8.5
190
6 - - 59.9
186
6 - - 10.9
238
6
3D
4upaA02 - 31.2
185
6 - - 8.9
194
5 - - 54.0
193
5 - - 17.6
192
5 - - 3.5
198
5 - - 65.2
195
5 - - 1.1
196
5 - - 2.1
206
4 - - 10.4
211
4 - - 16.8
205
4 - - 20.5
213
4 - - 60.7
200
4 - - 8.4
212
4 - - 0.0
207
4 - - 9.3
215
4 - - 37.9
208
4 - - 8.4
199
4 - - 7.5
202
4 - - 9.6
201
4 - - 7.6
214
Asp/Asn
4 - - 62.8
203
4 - - 7.2
204
4 - - 0.0
209
4 - - 0.0
210
4 - - 6.4
220
3 - - 13.3
226
3 - - 3.5
236
3 - - 2.8
218
3 - - 33.3
234
3 - - 7.3
221
3 - - 0.0
237
3 - - 40.7
235
3 - - 1.5
224
3 - - 52.9
232
3 - - 11.3
225
3 - - 8.5
233
3 - - 7.2
230
3 - - 2.2
229
3 - - 12.2
222
3 - - 7.9
217
3 - - 13.3
239
3 - - 66.3
231
3 - - 5.6
228
3 - - 10.9
223
3 - - 4.3
216
3 - - 0.0
219
3 - - 6.6
285
2 - - 0.0
288
2 - - 1.4
244
2 - - 0.0
246
2 - - 1.2
295
2 - - 8.7
260
2 - - 0.0
309
2 - - 40.5
300
2 - - 0.0
286
2 - - 0.0
308
2 - - 46.0
254
2 - - 24.0
301
2 - - 0.0
296
2 - - 5.6
265
2 - - 6.9
272
2 - - 0.0
287
2 - - 0.7
294
2 - - 0.0
275
2 - - 31.5
262
D, K and N
2 - - 7.9
251
2 - - 16.2
279
2 - - 21.0
256
2 - - 0.5
264
2 - - 0.0
255
2 - - 2.4
263
2 - - 0.0
293
2 - - 5.4
274
2 - - 3.2
303
2 - - 31.7
250
2 - - 26.4
278
2 - - 17.9
245
2 - - 0.0
267
2 - - 2.4
257
2 - - 0.5
276
2 - - 31.9
259
2 - - 0.0
292
2 - - 6.0
291
2 - - 1.3
241
2 - - 0.0
280
2 - - 15.1
273
2 - - 0.0
249
2 - - 3.1
307
2 - - 42.5
270
2 - - 1.9
299
2 - - 0.0
266
2 - - 47.3
302
AFU_orthologue AFUA_1G10750
2 - - 37.2
305
2 - - 32.4
281
2 - - 22.6
269
2 - - 0.5
298
2 - - 0.0
243
2 - - 1.7
261
2 - - 2.2
284
2 - - 9.1
247
2 - - 35.1
289
2 - - 14.4
268
2 - - 0.5
282
2 - - 0.0
253
2 - - 34.0
297
2 - - 0.0
277
2 - - 26.5
290
2 - - 15.9
304
2 - - 35.2
258
2 - - 0.0
306
2 - - 18.2
252
2 - - 23.5
283
2 - - 0.0
271
2 - - 8.5
248
2 - - 36.2
242
2 - - 16.4
358
1 - - 0.0
331
1 - - 0.0
325
1 - - 0.0
378
1 - - 0.0
350
1 - - 0.0
431
1 - - 0.0
337
1 - - 0.0
382
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
389
1 - - 0.0
418
1 - - 0.0
348
1 - - 0.0
364
1 - - 0.0
388
1 - - 0.0
367
1 - - 0.0
391
1 - - 0.0
324
1 - - 0.0
351
1 - - 0.0
410
1 - - 0.0
430
1 - - 0.0
379
1 - - 0.0
415
1 - - 0.0
342
1 - - 0.0
341
1 - - 0.0
417
1 - - 0.0
312
1 - - 0.0
405
1 - - 0.0
370
1 - - 0.0
416
1 - - 0.0
380
1 - - 0.0
381
1 - - 0.0
392
1 - - 0.0
373
1 - - 0.0
399
1 - - 0.0
436
1 - - 0.0
386
1 - - 0.0
366
1 - - 0.0
329
1 - - 0.0
400
1 - - 0.0
413
1 - - 0.0
349
1 - - 0.0
432
1 - - 0.0
346
1 - - 0.0
427
1 - - 0.0
333
1 - - 0.0
323
1 - - 0.0
352
1 - - 0.0
426
1 - - 0.0
369
1 - - 0.0
372
DNA directed
1 - - 0.0
428
1 - - 0.0
359
1 - - 0.0
414
1 - - 0.0
330
1 - - 0.0
394
1 - - 0.0
360
putative
1 - - 0.0
393
1 - - 0.0
322
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
310
1 - - 0.0
387
1 - - 0.0
354
1 - - 0.0
332
1 - - 0.0
425
1 - - 0.0
368
1 - - 0.0
424
1 - - 0.0
316
1 - - 0.0
395
1 - - 0.0
347
1 - - 0.0
434
1 - - 0.0
374
1 - - 0.0
429
1 - - 0.0
409
1 - - 0.0
327
1 - - 0.0
320
1 - - 0.0
361
1 - - 0.0
412
1 - - 0.0
385
1 - - 0.0
314
1 - - 0.0
355
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
433
1 - - 0.0
334
1 - - 0.0
377
1 - - 0.0
423
1 - - 0.0
422
1 - - 0.0
315
1 - - 0.0
402
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
363
1 - - 0.0
362
1 - - 0.0
317
1 - - 0.0
411
1 - - 0.0
398
1 - - 0.0
384
1 - - 0.0
407
1 - - 0.0
376
1 - - 0.0
313
1 - - 0.0
343
1 - - 0.0
397
1 - - 0.0
321
1 - - 0.0
371
1 - - 0.0
435
1 - - 0.0
401
1 - - 0.0
339
1 - - 0.0
345
1 - - 0.0
319
1 - - 0.0
404
1 - - 0.0
420
1 - - 0.0
344
1 - - 0.0
357
1 - - 0.0
336
1 - - 0.0
383
1 - - 0.0
419
1 - - 0.0
406
1 - - 0.0
396
1 - - 0.0
365
1 - - 0.0
403
1 - - 0.0
421
1 - - 0.0
318
1 - - 0.0
390
1 - - 0.0
356
1 - - 0.0
408
1 - - 0.0