The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Potassium Channel Kv1.1; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25: B-cell lymphoma 6 protein-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
3 P41182 (/IDA) P41183 (/IDA) P41183 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P41182 (/IPI) P41183 (/IPI) P41183 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 P41182 (/IDA) P41183 (/IDA) P41183 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 P41183 (/IDA) P41183 (/IDA)
Intronic transcription regulatory region sequence-specific DNA binding GO:0001161
Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcription of the transcript it is contained within.
2 P41183 (/IDA) P41183 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P41183 (/IDA) P41183 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P41183 (/IDA) P41183 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 P41183 (/ISO) P41183 (/ISO)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 P41183 (/ISO) P41183 (/ISO)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
2 P41183 (/IDA) P41183 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P41183 (/ISO) P41183 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 P41183 (/ISO) P41183 (/ISO)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 P41182 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 P41182 (/NAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 E1B8E6 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 P41182 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P41182 (/IPI)

There are 83 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
5 A0A2R8Q3C5 (/IGI) A0A2R8QM88 (/IGI) A0A2R8RQ09 (/IGI) F1R5N6 (/IGI) Q6PC08 (/IGI)
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
5 A0A2R8Q3C5 (/IMP) A0A2R8QM88 (/IMP) A0A2R8RQ09 (/IMP) F1R5N6 (/IMP) Q6PC08 (/IMP)
Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254
Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
5 A0A2R8Q3C5 (/IMP) A0A2R8QM88 (/IMP) A0A2R8RQ09 (/IMP) F1R5N6 (/IMP) Q6PC08 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 P41182 (/IDA) P41183 (/IDA) P41183 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of cell-matrix adhesion GO:0001953
Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Germinal center formation GO:0002467
The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of type 2 immune response GO:0002829
Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
B cell differentiation GO:0030183
The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of mast cell cytokine production GO:0032764
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Regulation of memory T cell differentiation GO:0043380
Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of isotype switching to IgE isotypes GO:0048294
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Positive regulation of cellular component movement GO:0051272
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P41183 (/IGI) P41183 (/IGI)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P41183 (/ISO) P41183 (/ISO)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
2 P41183 (/IGI) P41183 (/IGI)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of cell-matrix adhesion GO:0001953
Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
2 P41183 (/IMP) P41183 (/IMP)
Germinal center formation GO:0002467
The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of type 2 immune response GO:0002829
Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.
2 P41183 (/IGI) P41183 (/IGI)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P41183 (/IGI) P41183 (/IGI)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2 P41183 (/ISO) P41183 (/ISO)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2 P41183 (/IGI) P41183 (/IGI)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 P41183 (/IMP) P41183 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 P41183 (/IMP) P41183 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 P41183 (/IMP) P41183 (/IMP)
B cell differentiation GO:0030183
The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
2 P41183 (/IGI) P41183 (/IGI)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
2 P41183 (/ISO) P41183 (/ISO)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
2 P41183 (/IMP) P41183 (/IMP)
Positive regulation of histone deacetylation GO:0031065
Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
2 P41183 (/IGI) P41183 (/IGI)
Negative regulation of mast cell cytokine production GO:0032764
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
2 P41183 (/IMP) P41183 (/IMP)
Type 2 immune response GO:0042092
An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
2 P41183 (/IMP) P41183 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 P41183 (/IMP) P41183 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P41183 (/ISO) P41183 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P41183 (/IDA) P41183 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P41183 (/IMP) P41183 (/IMP)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
2 P41183 (/IMP) P41183 (/IMP)
Regulation of memory T cell differentiation GO:0043380
Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
2 P41183 (/IMP) P41183 (/IMP)
Positive regulation of regulatory T cell differentiation GO:0045591
Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
2 P41183 (/ISO) P41183 (/ISO)
Negative regulation of cell differentiation GO:0045596
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of T-helper 2 cell differentiation GO:0045629
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
2 P41183 (/IGI) P41183 (/IGI)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
2 P41183 (/IDA) P41183 (/IDA)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
2 P41183 (/IGI) P41183 (/IGI)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P41183 (/ISO) P41183 (/ISO)
Negative regulation of isotype switching to IgE isotypes GO:0048294
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
2 P41183 (/IGI) P41183 (/IGI)
Negative regulation of isotype switching to IgE isotypes GO:0048294
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
2 P41183 (/IMP) P41183 (/IMP)
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
2 P41183 (/IMP) P41183 (/IMP)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
2 P41183 (/IMP) P41183 (/IMP)
Positive regulation of cellular component movement GO:0051272
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
2 P41183 (/IMP) P41183 (/IMP)
Negative regulation of cellular senescence GO:2000773
Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.
2 P41183 (/IMP) P41183 (/IMP)
Regulation of germinal center formation GO:0002634
Any process that modulates the frequency, rate, or extent of germinal center formation.
1 P41182 (/NAS)
Negative regulation of B cell apoptotic process GO:0002903
Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.
1 P41182 (/NAS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 P41182 (/IDA)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P41182 (/TAS)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
1 P41182 (/IDA)
Type 2 immune response GO:0042092
An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
1 E1B8E6 (/ISS)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 P41182 (/TAS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P41182 (/IDA)
Positive regulation of regulatory T cell differentiation GO:0045591
Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
1 P41182 (/IMP)
Negative regulation of T-helper 2 cell differentiation GO:0045629
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
1 E1B8E6 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P41182 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P41182 (/NAS)
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 P41182 (/NAS)
Negative regulation of mitotic cell cycle DNA replication GO:1903464
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.
1 P41182 (/NAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P41182 (/IDA) P41183 (/IDA) P41183 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 E1B8E6 (/ISS) Q5RB65 (/ISS) Q5ZM39 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P41183 (/ISO) P41183 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P41183 (/ISO) P41183 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 P41183 (/ISO) P41183 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P41182 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P41182 (/TAS)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 P41182 (/IDA)