The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 422: serine/arginine-rich splicing factor 12
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
7 | Q8WXF0 (/HDA) Q8WXF0 (/HDA) Q8WXF0 (/HDA) Q8WXF0 (/HDA) Q8WXF0 (/HDA) Q8WXF0 (/HDA) Q8WXF0 (/HDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
7 | Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) |
|
RS domain binding GO:0050733
Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.
|
7 | Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
7 | Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Spliceosomal tri-snRNP complex assembly GO:0000244
The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
|
7 | Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) Q8WXF0 (/NAS) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
7 | Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) |
|
MRNA 5'-splice site recognition GO:0000395
Recognition of the intron 5'-splice site by components of the assembling spliceosome.
|
7 | Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) Q8WXF0 (/IDA) |
|
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
|
7 | Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) Q8WXF0 (/ISS) |