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CATH Superfamily 3.30.497.10

Antithrombin, subunit I, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Antithrombin, subunit I, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Serpin family B member 7

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Serine-type endopeptidase inhibitor activity GO:0004867
Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
 3 O75635 (/TAS) O75635 (/TAS) O75635 (/TAS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transforming growth factor beta1 production GO:0032914
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
 2 G3V6B5 (/IMP) Q920J5 (/IMP)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
 2 G3V6B5 (/IMP) Q920J5 (/IMP)
Positive regulation of glomerular mesangial cell proliferation GO:0072126
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
 2 G3V6B5 (/IMP) Q920J5 (/IMP)
Positive regulation of platelet-derived growth factor production GO:0090362
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
 2 G3V6B5 (/IMP) Q920J5 (/IMP)
Regulation of proteolysis GO:0030162
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
 1 Q9D695 (/ISO)
Positive regulation of transforming growth factor beta1 production GO:0032914
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
 1 Q9D695 (/ISO)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
 1 Q9D695 (/ISO)
Positive regulation of glomerular mesangial cell proliferation GO:0072126
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
 1 Q9D695 (/ISO)
Positive regulation of platelet-derived growth factor production GO:0090362
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
 1 Q9D695 (/ISO)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.