The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PAS domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 123: Dysfusion, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 A8JRD4 (/IPI) A8JRD5 (/IPI) Q2WGN8 (/IPI) Q6RZA5 (/IPI) Q9VBH3 (/IPI)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 A8JRD4 (/ISS) A8JRD5 (/ISS) Q2WGN8 (/ISS) Q6RZA5 (/ISS) Q9VBH3 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
5 A8JRD4 (/IDA) A8JRD5 (/IDA) Q2WGN8 (/IDA) Q6RZA5 (/IDA) Q9VBH3 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
5 A8JRD4 (/IPI) A8JRD5 (/IPI) Q2WGN8 (/IPI) Q6RZA5 (/IPI) Q9VBH3 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
5 A8JRD4 (/TAS) A8JRD5 (/TAS) Q2WGN8 (/TAS) Q6RZA5 (/TAS) Q9VBH3 (/TAS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
5 A8JRD4 (/ISS) A8JRD5 (/ISS) Q2WGN8 (/ISS) Q6RZA5 (/ISS) Q9VBH3 (/ISS)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
5 A8JRD4 (/IDA) A8JRD5 (/IDA) Q2WGN8 (/IDA) Q6RZA5 (/IDA) Q9VBH3 (/IDA)
Epithelial cell migration, open tracheal system GO:0007427
The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
5 A8JRD4 (/IMP) A8JRD5 (/IMP) Q2WGN8 (/IMP) Q6RZA5 (/IMP) Q9VBH3 (/IMP)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
5 A8JRD4 (/IEP) A8JRD5 (/IEP) Q2WGN8 (/IEP) Q6RZA5 (/IEP) Q9VBH3 (/IEP)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
5 A8JRD4 (/IMP) A8JRD5 (/IMP) Q2WGN8 (/IMP) Q6RZA5 (/IMP) Q9VBH3 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 A8JRD4 (/IDA) A8JRD5 (/IDA) Q2WGN8 (/IDA) Q6RZA5 (/IDA) Q9VBH3 (/IDA)
Imaginal disc-derived leg joint morphogenesis GO:0016348
The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.
1 Q9VBH3 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A8JRD4 (/IC) A8JRD5 (/IC) Q2WGN8 (/IC) Q6RZA5 (/IC) Q9VBH3 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A8JRD4 (/IDA) A8JRD5 (/IDA) Q2WGN8 (/IDA) Q6RZA5 (/IDA) Q9VBH3 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
5 A8JRD4 (/IPI) A8JRD5 (/IPI) Q2WGN8 (/IPI) Q6RZA5 (/IPI) Q9VBH3 (/IPI)