The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 545: E3 ubiquitin-protein ligase RNF135

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q6QI24 (/IPI) Q8IUD6 (/IPI) Q9CWS1 (/IPI) Q9CWS1 (/IPI)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
3 Q5M929 (/ISS) Q9CWS1 (/ISS) Q9CWS1 (/ISS)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q8IUD6 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8IUD6 (/IPI)
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
1 Q8IUD6 (/IPI)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
3 Q5M929 (/ISS) Q9CWS1 (/ISS) Q9CWS1 (/ISS)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
3 Q5M929 (/ISS) Q9CWS1 (/ISS) Q9CWS1 (/ISS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
3 Q5M929 (/ISS) Q9CWS1 (/ISS) Q9CWS1 (/ISS)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q8IUD6 (/IDA)
Negative regulation of type I interferon production GO:0032480
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 Q8IUD6 (/TAS)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
1 Q8IUD6 (/IMP)
Establishment of mitochondrion localization by microtubule attachment GO:0034640
The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.
1 Q6QI24 (/IMP)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
1 Q8IUD6 (/TAS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q8IUD6 (/IMP)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
1 Q6QI24 (/IMP)
Regulation of organelle transport along microtubule GO:1902513
Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
1 Q6QI24 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q5M929 (/ISS) Q9CWS1 (/ISS) Q9CWS1 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9CWS1 (/ISO) Q9CWS1 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8IUD6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8IUD6 (/TAS)