The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 226: E3 ubiquitin ligase BIG BROTHER

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
2 Q8L649 (/IDA) Q8L649 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q8L649 (/IPI) Q8L649 (/IPI)
Ubiquitin conjugating enzyme binding GO:0031624
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
2 Q8L649 (/IPI) Q8L649 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 Q8L649 (/IMP) Q8L649 (/IMP)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
2 Q8L649 (/IDA) Q8L649 (/IDA)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
2 Q8L649 (/IMP) Q8L649 (/IMP)
Floral organ development GO:0048437
The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.
2 Q8L649 (/IMP) Q8L649 (/IMP)
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
2 Q8L649 (/IDA) Q8L649 (/IDA)
Positive regulation of leaf senescence GO:1900057
Any process that activates or increases the frequency, rate or extent of leaf senescence.
2 Q8L649 (/IMP) Q8L649 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.