The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 1110: E3 ubiquitin-protein ligase ORTHRUS 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
2 | Q8VYZ0 (/ISS) Q9FVS2 (/ISS) |
|
Methyl-CpG binding GO:0008327
Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide.
|
2 | Q8VYZ0 (/ISS) Q9FVS2 (/ISS) |
|
Methyl-CpNpG binding GO:0010428
Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.
|
2 | Q8VYZ0 (/ISS) Q9FVS2 (/ISS) |
|
Methyl-CpNpN binding GO:0010429
Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.
|
2 | Q8VYZ0 (/ISS) Q9FVS2 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q8VYZ0 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q8VYZ0 (/IDA) |
|
Methyl-CpG binding GO:0008327
Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide.
|
1 | Q8VYZ0 (/IDA) |
|
Double-stranded methylated DNA binding GO:0010385
Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
|
1 | Q8VYZ0 (/IDA) |
|
Methyl-CpNpG binding GO:0010428
Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.
|
1 | Q8VYZ0 (/IDA) |
|
Methyl-CpNpN binding GO:0010429
Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.
|
1 | Q8VYZ0 (/IDA) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q8VYZ0 (/IPI) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q9FVS2 (/ISS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
2 | Q8VYZ0 (/ISS) Q9FVS2 (/ISS) |
|
DNA methylation on cytosine within a CG sequence GO:0010424
The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.
|
1 | Q8VYZ0 (/IMP) |
|
DNA methylation on cytosine within a CG sequence GO:0010424
The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.
|
1 | Q9FVS2 (/ISS) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q8VYZ0 (/IDA) |
|
Pericentric heterochromatin assembly GO:0031508
The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
|
1 | Q8VYZ0 (/IMP) |
|
DNA methylation on cytosine GO:0032776
The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
|
1 | Q8VYZ0 (/IMP) |
|
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
|
1 | Q8VYZ0 (/IDA) |
|
Positive regulation of methylation-dependent chromatin silencing GO:0090309
Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
|
1 | Q8VYZ0 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8VYZ0 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9FVS2 (/ISS) |
|
Chromocenter GO:0010369
A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure.
|
1 | Q8VYZ0 (/IDA) |