The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 294: Map kinase kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MAP kinase kinase activity GO:0004708
Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.
15 P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32491 (/ISS) P32491 (/ISS) P32491 (/ISS)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 P32490 (/IPI) P32490 (/IPI) P32490 (/IPI) P32490 (/IPI) P32490 (/IPI) P32490 (/IPI) P32490 (/IPI) P32491 (/IPI) P32491 (/IPI) P32491 (/IPI)
(5 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
7 P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall integrity MAPK cascade GO:0000196
A MAPK cascade that contributes to cell wall organization or biogenesis.
15 P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32491 (/IGI) P32491 (/IGI) P32491 (/IGI)
(5 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
15 P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32490 (/ISS) P32491 (/ISS) P32491 (/ISS) P32491 (/ISS)
(5 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
15 P32490 (/IMP) P32490 (/IMP) P32490 (/IMP) P32490 (/IMP) P32490 (/IMP) P32490 (/IMP) P32490 (/IMP) P32491 (/IMP) P32491 (/IMP) P32491 (/IMP)
(5 more)
Autophagy of peroxisome GO:0030242
The process in which peroxisomes are delivered to the vacuole and degraded in response to changing nutrient conditions.
15 P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32491 (/IGI) P32491 (/IGI) P32491 (/IGI)
(5 more)
Regulation of fungal-type cell wall organization GO:0060237
Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
15 P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32490 (/IGI) P32491 (/IGI) P32491 (/IGI) P32491 (/IGI)
(5 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
7 P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA) P32490 (/HDA)
Activation of MAPK activity involved in cell wall organization or biogenesis GO:0000199
Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Regulation of cell-substrate adhesion GO:0010810
Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Regulation of melanin biosynthetic process GO:0048021
Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Cellular heat acclimation GO:0070370
Any process that increases heat tolerance of a cell in response to high temperatures.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)
Cellular response to alkaline pH GO:0071469
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
4 Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP) Q4WJJ0 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
15 P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32491 (/IDA) P32491 (/IDA) P32491 (/IDA)
(5 more)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
15 P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32491 (/IDA) P32491 (/IDA) P32491 (/IDA)
(5 more)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
15 P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32491 (/IDA) P32491 (/IDA) P32491 (/IDA)
(5 more)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
15 P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32490 (/IDA) P32491 (/IDA) P32491 (/IDA) P32491 (/IDA)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P32491 (/HDA) P32491 (/HDA) P32491 (/HDA) P32491 (/HDA) P32491 (/HDA) P32491 (/HDA) P32491 (/HDA) P32491 (/HDA)