The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: H/ACA ribonucleoprotein complex subunit NHP2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI)
Box H/ACA snoRNA binding GO:0034513
Interacting selectively and non-covalently with box H/ACA small nucleolar RNA.
7 P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
1 Q9P7H0 (/IC)
Box H/ACA snoRNA binding GO:0034513
Interacting selectively and non-covalently with box H/ACA small nucleolar RNA.
1 Q9P7H0 (/IGI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cleavage involved in rRNA processing GO:0000469
Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
7 P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP)
Box H/ACA snoRNP assembly GO:0000493
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
7 P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP)
RRNA pseudouridine synthesis GO:0031118
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
7 P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP)
SnRNA pseudouridine synthesis GO:0031120
The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
7 P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA)
SnRNA pseudouridine synthesis GO:0031120
The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
7 P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP) P32495 (/IMP)
RRNA pseudouridine synthesis GO:0031118
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
3 Q9LEY9 (/ISS) Q9LEY9 (/ISS) Q9P7H0 (/ISS)
RRNA pseudouridine synthesis GO:0031118
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
1 Q9P7H0 (/IGI)
SnRNA pseudouridine synthesis GO:0031120
The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
1 Q9P7H0 (/IGI)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
10 P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) Q9LEY9 (/IDA) Q9LEY9 (/IDA) Q9P7H0 (/IDA)
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
7 P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA)
Box H/ACA snoRNP complex GO:0031429
A box H/ACA RNP complex that is located in the nucleolus.
7 P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA) P32495 (/IDA)
Box H/ACA snoRNP complex GO:0031429
A box H/ACA RNP complex that is located in the nucleolus.
7 P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI) P32495 (/IPI)
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
3 Q9LEY9 (/ISS) Q9LEY9 (/ISS) Q9P7H0 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9P7H0 (/HDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9P7H0 (/HDA)
Box H/ACA snoRNP complex GO:0031429
A box H/ACA RNP complex that is located in the nucleolus.
1 Q9P7H0 (/IGI)