The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glycosidases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 120: Alpha-amylase A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
8 P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B4 (/IGI) P0C1B4 (/IGI) P0C1B4 (/IGI)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
6 O13996 (/ISM) O14154 (/ISM) O74922 (/ISM) Q09840 (/ISM) Q10427 (/ISM) Q9Y7S9 (/ISM)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
3 Q7LV45 (/IDA) Q7LV45 (/IDA) Q7LV45 (/IDA)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
3 G5EAT0 (/RCA) G5EAT0 (/RCA) G5EAT0 (/RCA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
3 Q7LV45 (/IDA) Q7LV45 (/IDA) Q7LV45 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 O14154 (/NAS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
8 P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B3 (/IGI) P0C1B4 (/IGI) P0C1B4 (/IGI) P0C1B4 (/IGI)
Starch metabolic process GO:0005982
The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.
3 G5EAT0 (/IEP) G5EAT0 (/IEP) G5EAT0 (/IEP)
Starch metabolic process GO:0005982
The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.
3 G5EAT0 (/RCA) G5EAT0 (/RCA) G5EAT0 (/RCA)
Fungal-type cell wall biogenesis GO:0009272
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.
2 O74922 (/ISS) Q09840 (/ISS)
Fungal-type cell wall organization or biogenesis GO:0071852
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.
2 O13996 (/IC) O14154 (/IC)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q09840 (/ISS)
Fungal-type cell wall biogenesis GO:0009272
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.
1 Q9Y7S9 (/IMP)
Ascospore wall assembly GO:0030476
The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.
1 Q9Y7S9 (/IMP)
Extracellular polysaccharide metabolic process GO:0046379
The chemical reactions and pathways involving polysaccharides used in extracellular structures.
1 Q10427 (/IC)
Ascospore wall biogenesis GO:0070591
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.
1 Q9Y7S9 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type cell wall GO:0009277
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
5 P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA)
Cell wall-bounded periplasmic space GO:0030287
The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.
5 P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA)
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
5 P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA)
Spitzenkorper GO:0031521
Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
5 P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA)
Hyphal septin band GO:0032163
A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
5 P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA) P0C1B3 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 P0C1B4 (/IDA) P0C1B4 (/IDA) P0C1B4 (/IDA)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
3 O14154 (/TAS) O74922 (/TAS) Q09840 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O13996 (/HDA) Q10427 (/HDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 O14154 (/HDA) O74922 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O13996 (/HDA) Q10427 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 O13996 (/IC) Q10427 (/IC)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 Q9Y7S9 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 O74922 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9Y7S9 (/IDA)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q9Y7S9 (/IC)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q9Y7S9 (/IDA)