The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 65: Hyaluronidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 30 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hyalurononglucosaminidase activity GO:0004415
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
49 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(39 more)
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Receptor signaling protein tyrosine kinase inhibitor activity GO:0030294
Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Hyaluronoglucuronidase activity GO:0033906
Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.
24 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(14 more)
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
23 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(13 more)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Hyaluronan synthase activity GO:0050501
Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine =
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Hyalurononglucosaminidase activity GO:0004415
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
13 C0HKM3 (/IDA) F1MZM9 (/IDA) O43820 (/IDA) O43820 (/IDA) P48794 (/IDA) P86100 (/IDA) Q05A56 (/IDA) Q05A56 (/IDA) Q12794 (/IDA) Q12794 (/IDA)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 O43820 (/IPI) O43820 (/IPI) Q12891 (/IPI) Q9Z2Q3 (/IPI)
Hyaluronoglucuronidase activity GO:0033906
Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.
4 O43820 (/IDA) O43820 (/IDA) Q12891 (/IDA) Q9Z2Q3 (/IDA)
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
3 O35632 (/IDA) O35632 (/IDA) Q12891 (/IDA)
Hyalurononglucosaminidase activity GO:0004415
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
3 G3V6V8 (/TAS) Q12891 (/TAS) Q2M3T9 (/TAS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 O35632 (/IPI) O35632 (/IPI) Q12891 (/IPI)
Hyaluronoglucuronidase activity GO:0033906
Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.
3 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO)
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
2 O35632 (/ISO) O35632 (/ISO)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 Q12794 (/IDA) Q12794 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 O35632 (/ISO) O35632 (/ISO)
Receptor signaling protein tyrosine kinase inhibitor activity GO:0030294
Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.
2 O35632 (/ISO) O35632 (/ISO)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
2 O35632 (/ISO) O35632 (/ISO)
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
2 O35632 (/IPI) O35632 (/IPI)
Hyaluronan synthase activity GO:0050501
Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine =
2 Q12794 (/IDA) Q12794 (/IDA)
Hyalurononglucosaminidase activity GO:0004415
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
1 P48794 (/IMP)
Hyalurononglucosaminidase activity GO:0004415
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
1 Q91ZJ9 (/ISO)
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
1 Q12891 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 Q91ZJ9 (/ISO)
Hexosaminidase activity GO:0015929
Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
1 G5ECE8 (/IDA)
Receptor signaling protein tyrosine kinase inhibitor activity GO:0030294
Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.
1 Q12891 (/IDA)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
1 Q12891 (/IPI)
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
1 Q12891 (/ISS)
Hyaluronan synthase activity GO:0050501
Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine =
1 Q91ZJ9 (/ISO)

There are 147 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hyaluronan catabolic process GO:0030214
The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
48 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(38 more)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
44 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(34 more)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Negative regulation of fibroblast migration GO:0010764
Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Transformation of host cell by virus GO:0019087
Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Positive regulation of urine volume GO:0035810
Any process that increases the amount of urine excreted from the body over a unit of time.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Monocyte activation GO:0042117
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Viral entry into host cell GO:0046718
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Negative regulation of protein tyrosine kinase activity GO:0061099
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Renal water absorption GO:0070295
A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
23 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(13 more)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Hyaluronan metabolic process GO:0030212
The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Hyaluronan biosynthetic process GO:0030213
The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Positive regulation of hyaluranon cable assembly GO:1900106
Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
9 O35632 (/IDA) O35632 (/IDA) O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA) Q8VEI3 (/IDA) Q91ZJ9 (/IDA)
Hyaluronan catabolic process GO:0030214
The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
8 F1MZM9 (/IDA) O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA) Q8VEI3 (/IDA) Q9Z2Q3 (/IDA)
Ovarian follicle atresia GO:0001552
A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Penetration of zona pellucida GO:0007341
The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
5 O43820 (/IEP) O43820 (/IEP) Q12794 (/IEP) Q12794 (/IEP) Q12891 (/IEP)
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
5 O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
5 O43820 (/IEP) O43820 (/IEP) Q12794 (/IEP) Q12794 (/IEP) Q12891 (/IEP)
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
5 O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Negative regulation of ovarian follicle development GO:2000355
Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
4 O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Hyaluronan catabolic process GO:0030214
The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
3 Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
3 O35632 (/ISO) O35632 (/ISO) Q91ZJ9 (/ISO)
Chondroitin sulfate catabolic process GO:0030207
The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
3 G5ECE8 (/IDA) Q05A56 (/IDA) Q05A56 (/IDA)
Hyaluronan catabolic process GO:0030214
The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
3 Q12794 (/TAS) Q12794 (/TAS) Q12891 (/TAS)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
3 Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
3 O35632 (/ISO) O35632 (/ISO) Q91ZJ9 (/ISO)
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
3 Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
3 O35632 (/ISO) O35632 (/ISO) Q91ZJ9 (/ISO)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
3 O43820 (/IEP) O43820 (/IEP) Q12891 (/IEP)
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
3 O35632 (/IDA) O35632 (/IDA) Q12891 (/IDA)
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2 O35632 (/IMP) O35632 (/IMP)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 P38567 (/TAS) P38567 (/TAS)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
2 O35632 (/ISO) O35632 (/ISO)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
2 G3V6V8 (/TAS) Q2M3T9 (/TAS)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
2 Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
2 P38567 (/TAS) P38567 (/TAS)
Penetration of zona pellucida GO:0007341
The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
2 P38568 (/IMP) Q8VEI3 (/IMP)
Multicellular organism aging GO:0010259
An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
2 O35632 (/IMP) O35632 (/IMP)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
2 Q12794 (/IDA) Q12794 (/IDA)
Negative regulation of fibroblast migration GO:0010764
Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
2 O35632 (/ISO) O35632 (/ISO)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
2 O35632 (/ISO) O35632 (/ISO)
Transformation of host cell by virus GO:0019087
Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
2 Q12891 (/IDA) Q9Z2Q3 (/IDA)
Transformation of host cell by virus GO:0019087
Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
2 O35632 (/ISO) O35632 (/ISO)
Chondroitin sulfate catabolic process GO:0030207
The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
2 Q12794 (/TAS) Q12794 (/TAS)
Hyaluronan metabolic process GO:0030212
The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
2 Q12794 (/IDA) Q12794 (/IDA)
Hyaluronan biosynthetic process GO:0030213
The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 Q12794 (/IMP) Q12794 (/IMP)
Sperm-egg recognition GO:0035036
The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.
2 P38567 (/TAS) P38567 (/TAS)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
2 Q12794 (/IDA) Q12794 (/IDA)
Monocyte activation GO:0042117
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2 O35632 (/ISO) O35632 (/ISO)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
2 O35632 (/IDA) O35632 (/IDA)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
2 O35632 (/ISO) O35632 (/ISO)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
2 Q12794 (/IMP) Q12794 (/IMP)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
2 Q12794 (/IMP) Q12794 (/IMP)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 O35632 (/IDA) O35632 (/IDA)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
2 Q12794 (/IDA) Q12794 (/IDA)
Viral entry into host cell GO:0046718
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
2 O35632 (/ISO) O35632 (/ISO)
Skeletal system morphogenesis GO:0048705
The process in which the anatomical structures of the skeleton are generated and organized.
2 O35632 (/IMP) O35632 (/IMP)
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
2 O35632 (/ISO) O35632 (/ISO)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
2 O35632 (/IDA) O35632 (/IDA)
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
2 O35632 (/ISO) O35632 (/ISO)
Multicellular organismal iron ion homeostasis GO:0060586
Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.
2 O35632 (/IMP) O35632 (/IMP)
Negative regulation of protein tyrosine kinase activity GO:0061099
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
2 O35632 (/ISO) O35632 (/ISO)
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
2 Q12794 (/IDA) Q12794 (/IDA)
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
2 O35632 (/ISO) O35632 (/ISO)
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of hyaluranon cable assembly GO:1900106
Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.
2 Q12794 (/IDA) Q12794 (/IDA)
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
2 O35632 (/ISO) O35632 (/ISO)
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
2 O35632 (/ISO) O35632 (/ISO)
Positive regulation of extrinsic apoptotic signaling pathway GO:2001238
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
2 O35632 (/IDA) O35632 (/IDA)
Positive regulation of extrinsic apoptotic signaling pathway GO:2001238
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
2 O35632 (/IMP) O35632 (/IMP)
Polysaccharide catabolic process GO:0000272
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
1 P86100 (/IDA)
Ovarian follicle atresia GO:0001552
A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.
1 Q8VEI3 (/IDA)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q9Z2Q3 (/IEP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q12891 (/ISS)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
1 Q12891 (/IDA)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q62803 (/TAS)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
1 P48794 (/IMP)
Penetration of zona pellucida GO:0007341
The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
1 Q812F3 (/IDA)
Fusion of sperm to egg plasma membrane involved in single fertilization GO:0007342
The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
1 Q62803 (/TAS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 P86100 (/IDA)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
1 Q91ZJ9 (/ISO)
Negative regulation of fibroblast migration GO:0010764
Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
1 Q12891 (/IDA)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
1 Q12891 (/IDA)
Hyaluronan metabolic process GO:0030212
The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
1 Q91ZJ9 (/ISO)
Hyaluronan biosynthetic process GO:0030213
The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
1 Q91ZJ9 (/ISO)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 Q91ZJ9 (/ISO)
Positive regulation of urine volume GO:0035810
Any process that increases the amount of urine excreted from the body over a unit of time.
1 Q9Z2Q3 (/IEP)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
1 Q91ZJ9 (/ISO)
Monocyte activation GO:0042117
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1 Q12891 (/IDA)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 Q12891 (/ISS)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
1 Q12891 (/IDA)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
1 Q91ZJ9 (/ISO)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
1 Q91ZJ9 (/ISO)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 Q91ZJ9 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q12891 (/ISS)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
1 Q91ZJ9 (/ISO)
Viral entry into host cell GO:0046718
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
1 Q9Z2Q3 (/IDA)
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
1 Q91ZJ9 (/ISO)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
1 Q12891 (/IDA)
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
1 Q12891 (/IDA)
Embryonic skeletal joint morphogenesis GO:0060272
The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.
1 Q91ZJ9 (/IMP)
Negative regulation of protein tyrosine kinase activity GO:0061099
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
1 Q12891 (/IDA)
Renal water absorption GO:0070295
A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
1 Q9Z2Q3 (/IEP)
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
1 Q91ZJ9 (/ISO)
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
1 Q91ZJ9 (/ISO)
Positive regulation of hyaluranon cable assembly GO:1900106
Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.
1 Q91ZJ9 (/ISO)
Negative regulation of ovarian follicle development GO:2000355
Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
1 Q8VEI3 (/IDA)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
1 Q8VEI3 (/IMP)
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
1 Q12891 (/IDA)
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
1 Q12891 (/IDA)
Positive regulation of extrinsic apoptotic signaling pathway GO:2001238
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
1 Q12891 (/ISS)

There are 63 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
52 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(42 more)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
47 D2HES6 (/ISS) D2HES7 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS)
(37 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
25 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(15 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Hyaluranon cable GO:0036117
A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
22 D2HES7 (/ISS) F7D6C8 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) F7GHW3 (/ISS) G1NXY0 (/ISS) G1R5P3 (/ISS) G1SPB4 (/ISS)
(12 more)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
22 D2HES6 (/ISS) E2R560 (/ISS) F1SPN8 (/ISS) F6SZA5 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7H9X1 (/ISS) F7HIH6 (/ISS) G1LZ00 (/ISS) G1NXY9 (/ISS)
(12 more)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
6 O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA) Q8VEI3 (/IDA)
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Acrosomal membrane GO:0002080
The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
5 O43820 (/IDA) O43820 (/IDA) Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
5 O35632 (/IDA) O35632 (/IDA) Q05A56 (/IDA) Q05A56 (/IDA) Q12891 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
5 O35632 (/IDA) O35632 (/IDA) P48794 (/IDA) Q12891 (/IDA) Q9Z2Q3 (/IDA)
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
5 O43820 (/ISS) O43820 (/ISS) Q5REQ1 (/ISS) Q6RHW2 (/ISS) Q76HM9 (/ISS)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
4 O35632 (/ISO) O35632 (/ISO) Q8VEI3 (/ISO) Q91ZJ9 (/ISO)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
4 O35632 (/IDA) O35632 (/IDA) Q12891 (/IDA) Q9Z2Q3 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
3 O35632 (/ISS) O35632 (/ISS) Q12891 (/ISS)
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
3 P48794 (/IDA) Q812F3 (/IDA) Q8VEI3 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q12794 (/IDA) Q12794 (/IDA) Q12891 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 O35632 (/ISO) O35632 (/ISO) Q91ZJ9 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P38567 (/TAS) P38567 (/TAS) Q12891 (/TAS)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2 O35632 (/ISO) O35632 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 C0HKM3 (/IDA) P86100 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q12794 (/IDA) Q12794 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O35632 (/ISO) O35632 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P48794 (/IDA) Q812F3 (/IDA)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
2 O35632 (/ISO) O35632 (/ISO)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
2 P48794 (/IDA) Q812F3 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 O35632 (/ISO) O35632 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 O35632 (/ISO) O35632 (/ISO)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
2 O35632 (/ISO) O35632 (/ISO)
Hyaluranon cable GO:0036117
A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
2 Q12794 (/IDA) Q12794 (/IDA)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
2 Q12794 (/TAS) Q12794 (/TAS)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2 O35632 (/ISO) O35632 (/ISO)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
2 O35632 (/ISO) O35632 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 O35632 (/ISO) O35632 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q12794 (/HDA) Q12794 (/HDA)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
2 O35632 (/IDA) O35632 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q9Z2Q3 (/IDA)
Inner acrosomal membrane GO:0002079
The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
1 P38568 (/IDA)
Acrosomal membrane GO:0002080
The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
1 Q8VEI3 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q91ZJ9 (/ISO)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q8VEI3 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q8VEI3 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q12891 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q12891 (/IDA)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
1 Q12891 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q12891 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 Q12891 (/IDA)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
1 Q12891 (/IDA)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q12891 (/IDA)
Hyaluranon cable GO:0036117
A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
1 Q91ZJ9 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q12891 (/IDA)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
1 Q12891 (/ISS)
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
1 Q8VEI3 (/IDA)