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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 59: N-ethylmaleimide reductase, FMN-linked

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
N-ethylmaleimide reductase activity GO:0008748
Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
Chromate reductase activity GO:0034567
Catalysis of the reaction: chromate = chromium (III).
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
Oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor GO:0046857
Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
N-ethylmaleimide reductase activity GO:0008748
Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.
 8 Q8E9V9 (/ISS) Q8EEC9 (/ISS) Q9KKV7 (/ISS) Q9KKV7 (/ISS) Q9KKV7 (/ISS) Q9KKV7 (/ISS) Q9KKV7 (/ISS) Q9KKV7 (/ISS)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
 8 Q5LQ81 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS) Q9KKV2 (/ISS)
Oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor GO:0016657
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
 2 E9AGH7 (/IDA) E9AGH7 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
Nitroglycerin metabolic process GO:0018937
The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.
 52 P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(42 more)
2,4,6-trinitrotoluene catabolic process GO:0046256
The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.
 52 P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP) P77258 (/IMP)
(42 more)
Xenobiotic catabolic process GO:0042178
The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
 1 Q5LQ81 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 54 E9AGH7 (/IDA) E9AGH7 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA) P77258 (/IDA)
(44 more)