The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 29: L-lactate dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
51 |
O52792 (/IDA)
O52792 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
(41 more) |
|
L-lactate dehydrogenase activity GO:0004459
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
|
49 |
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
(39 more) |
|
L-lactate dehydrogenase (cytochrome) activity GO:0004460
Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
|
6 | Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) |
|
Oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor GO:0016899
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.
|
2 | O52792 (/IDA) O52792 (/IDA) |
|
L-lactate dehydrogenase activity GO:0004459
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
|
1 | Q5LV89 (/ISS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
|
49 |
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
(39 more) |
|
Lactate oxidation GO:0019516
The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.
|
49 |
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
P33232 (/IMP)
(39 more) |
|
L-fucose catabolic process GO:0042355
The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
|
49 |
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
P33232 (/IEP)
(39 more) |
|
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
6 | Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) Q9KKW6 (/ISS) |
|
Vancomycin biosynthetic process GO:0033072
The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-
|
2 | O52792 (/IDA) O52792 (/IDA) |
|
Lactate metabolic process GO:0006089
The chemical reactions and pathways involving lactate, the anion of lactic acid.
|
1 | Q5LV89 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
49 |
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
P33232 (/IDA)
(39 more) |