View in Gene3D

CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 134: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthas...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase. [EC: 4.3.1.32]
5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + NH(3) + L-methionine + 5'-deoxyadenosine.
  • The enzyme produces the F(0) precursor of the redox cofactor coenzyme F420, which is found in methanogens and in various actinobacteria.
  • F(0) is also produced by some cyanobacteria and eukaryotes.
  • The enzyme, which forms a complex with EC 2.5.1.147, is a radical SAM enzyme that uses the 5'-deoxyadenosyl radical to catalyze the condensation reaction.
  • Formerly EC 2.5.1.77.
 75 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3MVE0 A0A0H3MVE0
(65 more...)
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase. [EC: 2.5.1.147]
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine.
  • The enzyme is involved in the production of 7,8-didemethyl-8-hydroxy- 5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420, which is found in methanogens and in various actinobacteria.
  • FO is also produced by some cyanobacteria and eukaryotes.
  • The enzyme, which forms a complex with EC 4.3.1.32 is a radical SAM enzyme that uses the 5'-deoxyadenosyl radical to initiate the reaction.
  • Formerly EC 2.5.1.77.
 75 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3M5E8 A0A0H3MVE0 A0A0H3MVE0
(65 more...)