The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 114: Decarboxylase,orotidine phosphate

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Orotidine-5'-phosphate decarboxylase activity GO:0004590
Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
11 P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P10652 (/IMP) P13649 (/IMP)
(1 more)
Orotidine-5'-phosphate decarboxylase activity GO:0004590
Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
9 G5EDZ2 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA)
Orotidine-5'-phosphate decarboxylase activity GO:0004590
Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
4 P13649 (/IGI) P14965 (/IGI) P33283 (/IGI) P33283 (/IGI)
Orotidine-5'-phosphate decarboxylase activity GO:0004590
Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
2 P33283 (/ISA) P33283 (/ISA)
Orotate phosphoribosyltransferase activity GO:0004588
Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
1 G5EDZ2 (/IDA)
Orotidine-5'-phosphate decarboxylase activity GO:0004590
Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
1 P10652 (/RCA)

There are 33 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
'de novo' pyrimidine nucleobase biosynthetic process GO:0006207
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
9 P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P10652 (/IMP)
UMP biosynthetic process GO:0006222
The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
9 G5EDZ2 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP) P03962 (/IMP)
UMP biosynthetic process GO:0006222
The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
8 P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA)
'de novo' UMP biosynthetic process GO:0044205
The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
4 O13410 (/IMP) O13410 (/IMP) O13410 (/IMP) P14965 (/IMP)
'de novo' pyrimidine nucleobase biosynthetic process GO:0006207
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
3 P14965 (/IGI) P33283 (/IGI) P33283 (/IGI)
'de novo' pyrimidine nucleobase biosynthetic process GO:0006207
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
2 P33283 (/ISA) P33283 (/ISA)
Uracil biosynthetic process GO:0046107
The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
2 P33283 (/IMP) P33283 (/IMP)
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
1 G5EDZ2 (/IMP)
Sporocarp development involved in sexual reproduction GO:0000909
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
1 P10652 (/IMP)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
1 G5EDZ2 (/IMP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 P10652 (/RCA)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
1 G5EDZ2 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 G5EDZ2 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 P13649 (/IMP)
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 G5EDZ2 (/IMP)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 G5EDZ2 (/IGI)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 G5EDZ2 (/IMP)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
1 G5EDZ2 (/IMP)
Response to UV-C GO:0010225
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
1 G5EDZ2 (/IMP)
Response to gamma radiation GO:0010332
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
1 G5EDZ2 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 G5EDZ2 (/IMP)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 P13649 (/IMP)
Pyrimidine nucleobase biosynthetic process GO:0019856
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
1 G5EDZ2 (/IDA)
Pyrimidine nucleobase biosynthetic process GO:0019856
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
1 P13649 (/IGI)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 P13649 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 G5EDZ2 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
1 P13649 (/IMP)
Adhesion of symbiont to host GO:0044406
The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 P13649 (/IMP)
Uridine biosynthetic process GO:0046109
The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
1 P13649 (/IGI)
Uridine biosynthetic process GO:0046109
The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
1 P13649 (/IMP)
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
1 G5EDZ2 (/IMP)
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
1 A2QZ43 (/IMP)
Positive regulation of brood size GO:0090727
Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
1 G5EDZ2 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA) P03962 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P33283 (/IGI) P33283 (/IGI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P33283 (/ISA) P33283 (/ISA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P14965 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 G5EDZ2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P14965 (/HDA)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
1 P13649 (/IDA)