The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SRCR-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: CD6 molecule

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 G3V8U0 (/IPI) P30203 (/IPI) Q5FVU4 (/IPI) Q61003 (/IPI) Q812A4 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
3 G3V8U0 (/IDA) Q5FVU4 (/IDA) Q812A4 (/IDA)
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
1 P30203 (/IDA)
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
1 Q61003 (/ISO)
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
1 Q61003 (/ISS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 Q61003 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P30203 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q61003 (/ISO)
Lipoteichoic acid binding GO:0070891
Interacting selectively and non-covalently with lipoteichoic acid.
1 P30203 (/IMP)
Lipoteichoic acid binding GO:0070891
Interacting selectively and non-covalently with lipoteichoic acid.
1 Q61003 (/ISO)
Lipoteichoic acid binding GO:0070891
Interacting selectively and non-covalently with lipoteichoic acid.
1 Q61003 (/ISS)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
3 G3V8U0 (/IDA) Q5FVU4 (/IDA) Q812A4 (/IDA)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 P30203 (/IMP)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 Q61003 (/ISO)
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 Q61003 (/ISS)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 Q61003 (/ISO)
Acute inflammatory response to antigenic stimulus GO:0002438
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
1 P30203 (/IDA)
Acute inflammatory response to antigenic stimulus GO:0002438
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
1 Q61003 (/ISO)
Acute inflammatory response to antigenic stimulus GO:0002438
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
1 Q61003 (/ISS)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
1 P30203 (/IMP)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
1 Q61003 (/ISO)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
1 Q61003 (/ISS)
Lipopolysaccharide-mediated signaling pathway GO:0031663
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 P30203 (/IDA)
Lipopolysaccharide-mediated signaling pathway GO:0031663
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 Q61003 (/ISO)
Lipopolysaccharide-mediated signaling pathway GO:0031663
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 Q61003 (/ISS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P30203 (/IDA)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q61003 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q61003 (/ISS)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
1 P30203 (/IMP)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
1 Q61003 (/ISO)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
1 Q61003 (/ISS)
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
1 P30203 (/IDA)
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
1 Q61003 (/ISO)
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
1 Q61003 (/ISS)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
3 G3V8U0 (/IDA) Q5FVU4 (/IDA) Q812A4 (/IDA)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 P30203 (/IDA)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 Q61003 (/ISO)
Immunological synapse GO:0001772
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1 Q61003 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P30203 (/TAS)
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 P30203 (/IDA)
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 Q61003 (/ISO)
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 Q61003 (/ISS)
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
1 Q61003 (/ISO)