CATH Superfamily 3.10.20.90
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".
FunFam 390: UBP6p Ubiquitin-specific protease
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
10 | P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) P43593 (/IDA) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
10 | P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
10 | P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) P43593 (/IGI) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
10 | P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) |
|
Regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434
Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
10 | P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) |
|
Mitochondria-associated ubiquitin-dependent protein catabolic process GO:0072671
The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
|
10 | P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) |
|
Negative regulation of proteasomal protein catabolic process GO:1901799
Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
|
10 | P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) P43593 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteasome complex GO:0000502
A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
|
10 | P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) |
|
Proteasome regulatory particle GO:0005838
A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.
|
10 | P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) P43593 (/IPI) |