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CATH Superfamily 3.10.180.10

2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
4-hydroxyphenylpyruvate dioxygenase
616
3D
 1t47B02 - 89.0
2
Lactoylglutathione lyase
351
3D
 1fa8B00 - 57.3
3
Methylmalonyl-CoA epimerase, mitochondrial
236
3D
 3rmuD00 - 87.3
4
Lactoylglutathione lyase
147
3D
 6bnzA02 - 85.4
5
YecM family protein
120
3D
 1k4nA00 - 75.3
11
Lactoylglutathione lyase
115
3D
 4x2aB00 - 72.2
6
Methylmalonyl-CoA epimerase
112 - - 71.8
7
4-hydroxyphenylpyruvate dioxygenase
111
3D
 1cjxD02 - 82.2
13
4-hydroxyphenylpyruvate dioxygenase
105
3D
 6j63D02 - 88.1
8
4-hydroxyphenylpyruvate dioxygenase
95
3D
 5ec3A01 - 77.1
9
4-hydroxyphenylpyruvate dioxygenase
86 - - 12.3
10
Glyoxalase domain-containing protein 4
86
3D
 3zi1A02 - 69.6
15
Metallothiol transferase FosB
84
3D
 4jd1B01 - 38.2
12
2,3-dihydroxybiphenyl 1,2-dioxygenase
81
3D
 2zyqB02 - 37.0
14
glyoxalase domain-containing protein 4
66
3D
 3zi1A01 - 74.6
25
4-hydroxyphenylpyruvate dioxygenase
62
3D
 6j63D01 - 87.6
16
Methylmalonyl-CoA epimerase
56 - - 15.6
17
Methylmalonyl-CoA epimerase /ethylmalonyl-CoA epimerase
39 - - 28.3
27
1,2-dihydroxynaphthalene dioxygenase
38
3D
 2ei3A01 - 76.7
21
1,2-dihydroxynaphthalene dioxygenase
37
3D
 2ei3A02 - 41.1
22
4-hydroxyphenylpyruvate dioxygenase
36
3D
 5ec3A02 - 49.7
19
4-hydroxyphenylpyruvate dioxygenase
35 - - 40.9
18
4-hydroxyphenylpyruvate dioxygenase
35 - - 87.0
20
4-hydroxyphenylpyruvate dioxygenase
34 - - 84.3
24
2,3-dihydroxybiphenyl 1,2-dioxygenase
31
3D
 2zyqB01 - 44.1
23
Glyoxalase/bleomycin resistance/dioxygenase family protein
29 - - 30.5
26
Lactoylglutathione lyase
25 - - 70.4
28
Glyoxalase/fosfomycin resistance/dioxygenase domain containing protein
23 - - 34.0
31
Lactoylglutathione lyase
18 - - 7.3
30
Glyoxalase I
18 - - 1.0
29
Lactoylglutathione lyase
18 - - 7.7
32
Cadmium inducible protein CadI
17 - - 42.3
35
Glyoxalase I
16 - - 5.1
34
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
16 - - 84.3
33
Putative lyase
16 - - 42.2
36
Glyoxalase-like domain protein
15 - - 44.0
41
4-hydroxymandelate synthase
15
3D
 2r5vB02 - 44.8
40
Methylmalonyl-CoA epimerase
15
3D
 6bu2B00 - 17.5
39
Trihydroxytoluene oxygenase
AFU_orthologue AFUA_8G02470
14 - - 95.4
37
Catechol 2,3-dioxygenase
14 - - 26.9
43
27 kDa antigen Cfp30B
14
3D
 3oxhA02 - 5.9
38
3,4-dihydroxyphenylacetate 2,3-dioxygenase
14 - - 29.3
42
27 kDa antigen Cfp30B
14
3D
 3oxhA01 - 10.0
44
Methylmalonyl-CoA-ethylmalonyl-CoA epimerase protein
12 - - 22.4
45
ATP-dependent 6-phosphofructokinase
12 - - 12.9
46
4-hydroxyphenylpyruvate dioxygenase
11 - - 35.7
48
4-hydroxyphenylpyruvate dioxygenase
10 - - 41.3
47
Glyoxalase/bleomycin resistance protein/dioxygenase
10 - - 0.0
49
Catechol 2,3-dioxygenase
9 - - 21.5
50
Probable ring-cleaving dioxygenase
8 - - 8.3
52
4-hydroxyphenylpyruvate dioxygenase
8 - - 9.6
51
Putative enzyme related to lactoylglutathione lyase
8 - - 12.1
53
Lactoylglutathione lyase
7 - - 0.0
58
tRNA
guanine-N(1
7 - - 1.2
57
Biphenyl-2,3-diol 1,2-dioxygenase
7 - - 2.0
54
Catechol 2,3-dioxygenase
7 - - 0.0
55
Protein yecM
7 - - 0.0
56
Predicted enzyme related to lactoylglutathione lyase
7 - - 0.0
59
Glyoxalase-like domain-containing protein
6 - - 16.1
62
4-hydroxyphenylpyruvate dioxygenase
5 - - 46.2
60
Putative enzyme related to lactoylglutathione lyase
5 - - 0.0
63
ATP-dependent 6-phosphofructokinase
5 - - 8.7
61
Putative protein C31H2.4
5 - - 28.5
69
Glyoxalase
4 - - 9.5
67
Anthracycline biosynthesis protein DauV
4 - - 11.3
68
4-hydroxyphenylpyruvate dioxygenase
4 - - 30.1
66
Methylglyoxalase
4 - - 0.0
65
Methylmalonyl-CoA epimerase
4 - - 0.0
64
Lactoylglutathione lyase family protein
4 - - 30.0
88
4-hydroxymandelate synthase
3
3D
 2r5vA01 - 0.0
71
Lactoylglutathione lyase family protein
3 - - 2.0
74
ATP-dependent 6-phosphofructokinase
3 - - 0.0
115
Putative 4-hydroxyphenylpyruvic acid dioxygenase
3
3D
 3zgjB01 - 0.0
72
Anthracycline biosynthesis protein DnrV
3 - - 8.8
70
Methylmalonyl-CoA epimerase
3 - - 0.0
73
4-hydroxyphenylpyruvate dioxygenase, putative
3 - - 6.7
92
Uncharacterized protein
2 - - 2.3
76
Uncharacterized protein At5g48480
2 - - 10.3
83
Uncharacterized 4-hydroxyphenylpyruvate dioxygenase-like protein
2 - - 20.4
90
4-hydroxyphenylpyruvic acid dioxgenase
2 - - 0.0
75
Uncharacterized protein
2 - - 34.8
89
4-hydroxyphenylpyruvate dioxygenase
2 - - 0.0
82
Glr1161 protein
2 - - 0.0
87
4-hydroxyphenylpyruvate dioxygenase
2 - - 0.0
93
Uncharacterized protein
2 - - 5.0
80
SOS-regulated glyoxalase family protein
2 - - 0.0
77
Glyoxalase/bleomycin resistance protein/dioxygenase
2 - - 0.0
85
4-hydroxyphenylpyruvate dioxygenase
2 - - 19.1
79
Methylmalonyl-CoA epimerase
2 - - 8.4
96
Uncharacterized protein
2 - - 23.0
84
4-hydroxyphenylpyruvate dioxygenase
2 - - 14.6
91
4-hydroxyphenylpyruvic acid dioxgenase
2 - - 0.0
95
Putative N-acetyltransferase YjaB
2 - - 1.7
94
ATP-dependent 6-phosphofructokinase
2 - - 4.3
78
Methylmalonyl-CoA epimerase
2 - - 0.9
86
4-hydroxyphenylpyruvate dioxygenase
2 - - 0.0
81
Uncharacterized 4-hydroxyphenylpyruvate dioxygenase-like protein
2 - - 28.7
97
Biphenyl-2,3-diol 1,2-dioxygenase III
1 - - 0.0
114
Uncharacterized protein
1 - - 0.0
99
Glyoxalase family protein
1 - - 0.0
113
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
110
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
108
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
116
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
112
Uncharacterized protein
1 - - 0.0
98
Uncharacterized protein
1 - - 0.0
107
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
109
Uncharacterized protein
1 - - 0.0
101
Uncharacterized protein
1 - - 0.0
104
Gll3193 protein
1 - - 0.0
103
Glr0001 protein
1 - - 0.0
100
Glyoxalase family protein
1 - - 0.0
106
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
118
Uncharacterized protein
1 - - 0.0
102
Putative lyase
1 - - 0.0
119
ATP-dependent 6-phosphofructokinase
1 - - 0.0
105
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
117
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
111
4-hydroxyphenylpyruvate dioxygenase
1 - - 0.0
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